MAK491
Formate Assay Kit
sufficient for 100 colorimetric tests
Synonym(s):
Formate Test Kit
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About This Item
NACRES:
NA.84
UNSPSC Code:
12161503
Quality Level
application(s)
environmental
detection method
colorimetric
relevant disease(s)
neurological disorders
shipped in
wet ice
storage temp.
−20°C
General description
Formate is the anion derived from formic acid, the simplest carboxylic acid. It is also the metabolic byproduct of formaldehyde metabolism in the body, and the eventual metabolic byproduct of methanol, which is first broken down to formaldehyde. At high levels, formate is neurotoxic to the central nervous system and can cause blindness, coma, and death. Although naturally present in the body at low levels, elevated levels of formate may be used as an indicator of formaldehyde exposure and methanol poisoning.
Application
The kit is suitable for the determination of formate in biological samples such as urine and serum.
Biochem/physiol Actions
The Formate Assay Kit is based on the formate dehydrogenase catalyzed oxidation of formate, which generates carbon dioxide and NADH that reduces a formazan (MTT) dye. The intensity of the reduced MTT, measured at 565 nm, is directly proportional to the formate concentration in the sample.
Features and Benefits
- Linear detection range 0.050 to 5 mM formate.
- Compatible with high-throughput handling systems.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
Regulatory Information
常规特殊物品
低风险生物材料
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAK491-1KT | 04065269211914 |