MAK623
Farnesyltransferase Activity Assay Kit
sufficient for 400 fluorometric tests
Synonym(s):
FTase Activity Assay Kit
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
41116104
eCl@ss:
40050204
usage
sufficient for 400 fluorometric tests
detection method
fluorometric
storage temp.
−20°C
General description
Farnesyltransferase (FTase, EC 2.5.1.58) catalyzes the transfer of a farnesyl group from farnesylpyrophosphate to the cysteine residue of the C-terminus of target proteins. When not properly regulated, farnesylated proteins, including the Ras super family of small GTPases, can lead to developmental disorders and cancer.
Application
Suitable for the quantitative determination of FTase enzyme activity in biological samples.
Biochem/physiol Actions
In this assay, FTase reacts with farnesyl pyrophosphate and the dansyl-peptide substrate releasing a product that is measurable by fluorescence (λem/ex = 340/550 nm). The linear detection range is 0.024 – 3.2 U/LFTase.
Storage Class
10 - Combustible liquids
WGK
nwg
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.