Name: MISSION<SUP>®</SUP> miRNA Product Offerings
Brand: SIGMA

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<p><b>Synthetic miRNA Inhibitors (S-TuD) Negative Controls</b></p>


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<h2><br>
N-TER<sup>™</sup> Nanoparticle siRNA Transfection System</h2>


<h2>Lentiviral Library- Request A quote</h2>


<ul>
<li>Peptide transfection reagent for use in difficult to transfect cells</li>
</ul>


<h4>Lentiviral and Synthetic miRNA Negative Controls Measure transduction efficiency or monitor off-target effects.</h4>
<ul>
<li>All miRNA mimic and inhibitor negative controls are carefully selected, and have no known homology to known human or mouse gene sequences</li>
<li>Each negative control contains either a <i>Arabidopsis thaliana</i> sequence (Control 1) or a <i>Caenorhabditis elegans</i> sequence (Control 2)</li>
<li>Lenti TuD Negative controls available: <a href="/CN/en/product/sigma/HLTUD001C">HLTUD001C</a> and <a href="/CN/en/product/sigma/HLTUD002C">HLTUD002C</a></li>
<li>Lenti miR Negative Controls available: <a href="/CN/en/product/sigma/NCLMIR001">NCLMIR001</a> and <a href="/CN/en/product/sigma/NCLMIR002">NCLMIR002</a></li>
<li>Synthetic miRNA mimics Negative Controls available as <a href="/CN/en/product/sigma/HMC0002">HMC0002</a> and <a href="/CN/en/product/sigma/HMC0003">HMC0003</a></li>
<li>Synthetic miRNA Inhibitors Negative Controls available as <a href="/CN/en/product/sigma/NCSTUD001">NCSTUD001</a> and <a href="/CN/en/product/sigma/NCSTUD002">NCSTUD002</a></li>
</ul>


<h4>Bench-top transcriptome-wide human miRNA and ncRNA gene target identification.</h4>
<ul>
<li>Convenience: Perform dual screening with one vector due to the innovative dual selection cassette</li>
<li>Simplicity: 3 easy steps: Library Transfection, microRNA Transfection and Ganciclovir Selection, and PCR and Sequencing.</li>
<li>Relevance: The only method for genome-wide functional identification of miRNA targets</li>
<li>Custom miRNA mimic synthesis capabilities: custom species sequences, quantities, and modifications</li>
</ul>


<h4>Most comprehensible list of miRNA mimics</h4>
<ul>
<li>Designed using a proprietary algorithm based upon the Tough Decoy (TuD) design</li>
<li>Long-lasting inhibition at very low nM concentrations</li>
<li>Excellent resistance to cellular nucleases</li>
<li>Structure provides potent inhibition of the desired miRNA</li>
<li>Custom synthesis capabilities: custom species sequences, quantities, and modifications</li>
</ul>


<h4>Choose from over 3,000+ human and mouse miRNA inhibitors</h4>
<ul>
<li>Designed using a proprietary algorithm based upon the Tough Decoy (TuD) design</li>
<li>Allows for potent inhibition of the desired miRNA</li>
<li>Stable, long-term expression of miRNA</li>
<li>Efficient delivery of mimic into wide variety of cell types</li>
<li>Species include both human and mouse: 1,953 human lenti miRNA inhibitors and 1,214 mouse lenti miRNA inhibitors</li>
<li>Custom options available</li>
</ul>


<h4>Different gene pathway of interest? Want a more complete list?</h4>


<h4>Choose from over 2500+ miRNA mimics</h4>
<ul>
<li>Most comprehensive collection of miRNA human mimics available (mirBase ver. 21)</li>
<li>Available as a complete library or individual miRNA mimics</li>
<li>Stable, long-term expression of miRNA</li>
<li>Efficient delivery of mimic into wide variety of cell types</li>
<li>The ability to select for cells that express the miRNA of interest</li>
<li>Custom options available</li>
</ul>


<ul>
<li>Gene family sets are fully customizable allowing for complete flexibility to add or delete clone or gene content.</li>
</ul>


<h4>Validate miRNA targets and study post-transcriptional gene regulation with lentiviral 3′UTR reporters.</h4>
<ul>
<li>A genome-wide collection of pre-cloned reporter constructs for over 10,000 human 3’UTRs</li>
<li>Constructs are composed of a human 3’UTR fused to a novel luciferase reporter</li>
<li>Relevance: The only method for genome-wide functional identification of miRNA targets</li>
<li>Optimized Renilla luciferase delivers higher activity</li>
<li>System utilizes a lentiviral vector for delivery into difficult to transfect cell lines, including differentiated and non-dividing cells</li>
<li>Superb virus quality delivers superior performance</li>
<li>Negative controls, miRNA Mimics, and MISSION LightSwitch Luciferase Assay Reagent<sup>™</sup> are available to complete the validation workflow.</li>
</ul>


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MISSION® miRNA Product Offerings; Synonyms: Custom miRNA,Human miRNA cDNA Library,Lenti TuDs,Lentiviral miRNA mimics,MISSION® 3′UTR Lenti GoClone,MISSION® Lentiviral miRNA inhibitors,MISSION® LightSwitch Luciferase Assay Reagent,MISSION® Target ID Library,MISSION® miRNA Human inhibitors,MISSION® miRNA Human mimics,MISSION® miRNA Workflow,Synthetic TuDs,Synthetic miRNA inhibitors,Synthetic miRNA mimics,Tough Decoy Design,miRBase version 21,miRNA Identification,miRNA Library,miRNA Screening,miRNA Validation at Sigma-Aldrich

MISSION® miRNA Product Offerings | Sigma-Aldrich

MISSION<SUP>®</SUP> miRNA Product Offerings

MISSION<SUP>&#174;</SUP> miRNA Product Offerings

Synonym: Custom miRNA, Human miRNA cDNA Library, Lenti TuDs, Lentiviral miRNA mimics, MISSION® 3′UTR Lenti GoClone, MISSION® Lentiviral miRNA inhibitors, MISSION® LightSwitch Luciferase Assay Reagent, MISSION® Target ID Library, MISSION® miRNA Human inhibitors, MISSION® miRNA Human mimics, MISSION® miRNA Workflow, Synthetic TuDs, Synthetic miRNA inhibitors, Synthetic miRNA mimics, Tough Decoy Design, miRBase version 21, miRNA Identification, miRNA Library, miRNA Screening, miRNA Validation

SKU	GTIN
5331960001	04055977281507
5080576001	04061838338204
HMI2768-5NMOL	04061831390452
HMI2774-5NMOL	04061831390513
HMC0002-5NMOL	04061826762066
HMC0003-5NMOL	04061831392593
MI00300-1SET	04061834066484
17-10521	04053252984648

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MISSION^® miRNA Product Offerings

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