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N1165

Pimonidazole

Name: Pimonidazole
Brand: SIGMA

≥98% (HPLC), 2-nitroimidazole hypoxia marker, powder

Synonym(s):

NSC 380540, PD 126675;, Ro 03-8799;, alpha-((2-Nitroimidazol-1-yl)methyl)-1-piperidineethanol;, alpha-[(2-Nitro-1H-imidazol-1-yl)methyl]-1-piperidineethanol

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₈N₄O₃

CAS Number:

70132-50-2

Molecular Weight:

254.29

UNSPSC Code:

12352200

PubChem Substance ID:

329818508

NACRES:

NA.77

MDL number:

MFCD00867974

Assay:

≥98% (HPLC)

Form:

powder

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Properties

Product Name

Pimonidazole, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

yellow

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

OC(CN1CCCCC1)Cn2ccnc2[N+]([O-])=O

InChI

1S/C11H18N4O3/c16-10(8-13-5-2-1-3-6-13)9-14-7-4-12-11(14)15(17)18/h4,7,10,16H,1-3,5-6,8-9H2

InChI key

WVWOOAYQYLJEFD-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Pimonidazole possesses a nitro group at position 2 and an imidazole ring. Pimonidazole undergoes reduction and is activated in hypoxic cells.

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole forms adducts with thiol groups in proteins, peptides and amino acids.

Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

0000563185

0000518586

0000455613

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Global Trade Item Number

SKU	GTIN
N1165-50MG	04061834106852
N1165-10MG	04061832722955