Name: Nisoxetine hydrochloride
Brand: SIGMA

Sign Into View Organizational & Contract Pricing

About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₁NO₂ · HCl

CAS Number:

57754-86-6

Molecular Weight:

307.82

MDL number:

MFCD00153850

UNSPSC Code:

12352200

PubChem Substance ID:

24277788

NACRES:

NA.77

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Quality Level

100

Assay

≥98% (HPLC)

form

solid

storage condition

desiccated

color

white to beige

solubility

H₂O: 20 mg/mL
ethanol: 50 mg/mL

SMILES string

Cl[H].CNCCC(Oc1ccccc1OC)c2ccccc2

InChI

1S/C17H21NO2.ClH/c1-18-13-12-15(14-8-4-3-5-9-14)20-17-11-7-6-10-16(17)19-2;/h3-11,15,18H,12-13H2,1-2H3;1H

InChI key

LCEURBZEQJZUPV-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Nisoxetine has been used as a norepinephrine transport (NET) blocker in autoradiography studies. It has also been used as a NET blocker to study its effects on perivascular adipose tissue.

Biochem/physiol Actions

Nisoxetine is a selective and potent noradrenaline reuptake inhibitor. It has a high affinity towards the noradrenaline transporter. Nisoxetine possesses antidepressant activity.

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

0000293783

042M4604V

0000144840

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service