Anti-NeuroD1 antibody produced in rabbit

NeuroD1 gene is mapped to human chromosome 2q31.3.

Neuronal differentiation 1 (NEUROD1) is a transcription factor which is highly expressed in the brain, pancreas and retina.

synthetic peptide corresponding to amino acids 76-91 of human NeuroD1 conjugated to BSA. The corresponding sequence differs in mouse and rat by two and three amino acids, respectively.

Anti-NeuroD1 antibody produced in rabbit has been used in chromatin immunoprecipitation and immunoblotting.

Anti-NeuroD1 specifically recognizes human, mouse and rat NeuroD1.

NeuroD1 is a basic helix-loop-helix (bHLH) transcription factor, which regulates the fate of specific neuronal, endocrine and retinal cells.

Neuronal differentiation 1 (NEUROD1) binds to promoters and regulates gene expression. It can also enhance tumor cell survival in lung tumors. Mutations in the gene encoding NEUROD1 have been associated with neurological problems and early-onset diabetes.

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

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