N3905
Nicarbazin
Synonym(s):
N,N′-bis(4-Nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone
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About This Item
Empirical Formula (Hill Notation):
C13H10N4O5 · C6H8N2O
CAS Number:
Molecular Weight:
426.38
NACRES:
NA.85
PubChem Substance ID:
UNSPSC Code:
51102829
EC Number:
206-359-1
MDL number:
form
powder
antibiotic activity spectrum
parasites
mode of action
cell membrane | interferes
SMILES string
Cc1cc(C)nc(O)n1.[O-][N+](=O)c2ccc(NC(=O)Nc3ccc(cc3)[N+]([O-])=O)cc2
InChI
1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
InChI key
UKHWDRMMMYWSFL-UHFFFAOYSA-N
Application
Nicarbazin is a coccidiostat (antiprotozoal agent) in the poultry industry and is a contraceptive for resident Canada geese and waterfowl. It is used to study avian reproduction and is used to interfere with the formation of the vitelline (yolk) membrane in bird eggs. It has been used to study how delivery method can effect plasma levels of 4,4′-dinitrocarbanilide (DNC), which is the active anticoccidial component of Nicarbazin.
Biochem/physiol Actions
Nicarbazin affects avian reproduction by reducing egg production, egg weight, and egg hatchability. The mechanism of action of Nicarbazin is unknown.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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