N4377
4-Nitrophenyl valerate
chromogenic, ≥98% (TLC), liquid
Synonym(s):
Pentanoic acid 4-nitrophenyl ester
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About This Item
Empirical Formula (Hill Notation):
C11H13NO4
CAS Number:
Molecular Weight:
223.23
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83
MDL number:
Product Name
4-Nitrophenyl valerate, liquid
assay
≥98% (TLC)
Quality Level
form
liquid
color
faintly yellow to dark yellow
storage temp.
−20°C
SMILES string
CCCCC(=O)Oc1ccc(cc1)N(=O)=O
InChI
1S/C11H13NO4/c1-2-3-4-11(13)16-10-7-5-9(6-8-10)12(14)15/h5-8H,2-4H2,1H3
InChI key
RJQXEHRFVKJLJO-UHFFFAOYSA-N
Application
4-Nitrophenyl valerate has been used as a substrate solution to measure the rate of p-nitrophenol formation using p-nitrophenyl valerate as substrate. It has also been used as a substrate to measure general esterase activity in hepatopancreas extracts.
Biochem/physiol Actions
4-Nitrophenyl valerate acts as a model substrate for carboxylesterase and butyrylcholinesterase.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Lincoln A MacKenzie et al.
Toxicon : official journal of the International Society on Toxinology, 60(3), 406-419 (2012-05-23)
An enzyme capable of hydrolysing pectenotoxins (PTXs) and okadaic acid (OA) esters within the hepatopancreas of the Greenshell™ mussel Perna canaliculus was isolated and characterized. The enzyme was purified by sequential polyethylene glycol fractionation, anion exchange, hydrophobic interaction, gel filtration
Sonja Kübelbeck et al.
Macromolecular bioscience, 18(7), e1800095-e1800095 (2018-06-06)
Herein, the synthesis of enzyme-polymer conjugates is reported. Four different activated polymers (mPEG-aldehyde, mPEG-NHS, maltodextrin-aldehyde, carboxymethyl cellulose aldehyde) are conjugated to the surface of protease, α-amylase, and lipase using two different strategies (reductive amination and alkylation with NHS-activated acid). Although
Xia Wen et al.
Toxicology, 416, 15-22 (2019-01-28)
Hepatic carboxylesterases (Ces) catalyze the metabolism of drugs, environmental toxicants, and endogenous lipids and are known to be regulated by multiple nuclear receptors. Perfluorooctanoic acid (PFOA) is a synthetic fluorochemical that has been associated with dyslipidemia in exposed populations. In
Brittany N Szafran et al.
Molecules (Basel, Switzerland), 23(12) (2018-12-06)
Endocannabinoid-metabolizing enzymes are downregulated in response to lipopolysaccharide (LPS)-induced inflammation in mice, which may serve as a negative feedback mechanism to increase endocannabinoid levels and reduce inflammation. Increased plasma levels of the pro-inflammatory cytokine interleukin-6 (IL-6) and decreased fatty acid
Andrés M Attademo et al.
Ecotoxicology (London, England), 20(1), 274-282 (2010-11-30)
Activity of B-esterases (BChE: butyrylcholinesterase and CbE: carboxylesterase using two model substrates: α-naphthyl acetate and 4-nitrophenyl valerate) in a native frog, Leptodactylus chaquensis from rice fields (RF1: methamidophos and RF2: cypermethrin and endosulfan sprayed by aircraft) and non-contaminated area (pristine
Global Trade Item Number
| SKU | GTIN |
|---|---|
| N4377-10G | 04061835516162 |
| N4377-5G | 04061835516179 |
| N4377-1G | 04061834116547 |
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