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CN

N6125

Naphthol AS-TR phosphate disodium salt

fluorogenic, ≥99% (HPLC), powder

Synonym(s):

NASTRp disodium salt

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About This Item

Empirical Formula (Hill Notation):
C18H13ClNNa2O5P
CAS Number:
4264-93-1
Molecular Weight:
435.71
UNSPSC Code:
12352204
PubChem Substance ID:
24897766
NACRES:
NA.83
MDL number:
MFCD00069550

Key Documents

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Product Name

Naphthol AS-TR phosphate disodium salt, ≥99% (HPLC), Bulk package

SMILES string

[Na+].[Na+].Cc1cc(Cl)ccc1NC(=O)c2cc3ccccc3cc2OP([O-])([O-])=O

InChI key

TYCHZTPSWMGRRI-UHFFFAOYSA-L

InChI

1S/C18H15ClNO5P.2Na/c1-11-8-14(19)6-7-16(11)20-18(21)15-9-12-4-2-3-5-13(12)10-17(15)25-26(22,23)24;;/h2-10H,1H3,(H,20,21)(H2,22,23,24);;/q;2*+1/p-2

assay

≥99% (HPLC)

form

powder

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

Quality Level

300

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Application

Substrate for the histochemical demonstration of acid and alkaline phosphatase.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
0000498659
0000498659
0000497369
0000497369
0000461346

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Adéla Kratochvílová et al.
Scientific reports, 10(1), 7489-7489 (2020-05-06)
Caspases are proteases traditionally associated with inflammation and cell death. Recently, they have also been shown to modulate cell proliferation and differentiation. The aim of the current research was to search for osteogenic molecules affected by caspase inhibition and to specify
Eva Svandova et al.
Journal of anatomy, 235(2), 256-261 (2019-05-31)
FASL (CD178) is known for its role in triggering apoptosis, mostly in relation with immune cells but additional functions have been reported more recently, including those in bone development. Examination of postnatal FasL-deficient mice (gld) showed an increased bone deposition
Claire Chevalier et al.
STAR protocols, 2(2), 100452-100452 (2021-04-30)
Mesenchymal-derived osteoblasts play a key role in bone formation via synthesis and mineralization of the bone and bone remodeling. Osteoclasts are multinucleated cells of hematopoietic origin with a role in bone resorption. Here, we describe a protocol for generating primary
Barbora Vesela et al.
Frontiers in cell and developmental biology, 8, 589136-589136 (2020-11-13)
Caspases are evolutionary conserved proteases traditionally known as participating in apoptosis and inflammation but recently discovered also in association with other processes such as proliferation or differentiation. This investigation focuses on caspase-12, ranked among inflammatory caspases but displaying other, not
Veronika Oralová et al.
Biology open, 8(5) (2019-05-28)
Zebrafish is now widely used in biomedical research as a model for human diseases, but the relevance of the model depends on a rigorous analysis of the phenotypes obtained. Many zebrafish disease models, experimental techniques and manipulations take advantage of
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