N6523
Anti-Nephronophthisis (NPH) (pic) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 90 kDa
species reactivity
mouse
technique(s)
immunoprecipitation (IP): 10-20 μg/mL
western blot: 2-10 μg/mL
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
SMILES string
[H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2)C(O)=O)c34
InChI key
VGLIYJAMHMSYBY-NOZJJQNGSA-N
Gene Information
mouse ... Nphp1(53885)
Related Categories
General description
Nephronophthisis 1 homolog (Nph) is highly expressed in mouse testis.
Immunogen
GST fusion protein corresponding to amino acids 612-691 of mouse NPH.
Biochem/physiol Actions
Studies have shown that male mice with a mutant nephronophthisis 1 homolog (Nph) protein turn out to be infertile.
Physical form
Solution in phosphate buffered saline containing 0.08% sodium azide.
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Storage Class Code
10 - Combustible liquids
Regulatory Information
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Targeted disruption of Nphp1 causes male infertility due to defects in the later steps of sperm morphogenesis in mice.
Jiang ST
Human Molecular Genetics, 17(21), 3368-3379 (2008)
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Datasheet
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