Skip to Content
Merck
CN

N6784

Noggin/Fc Chimera from mouse

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

UNSPSC Code:
51111800
NACRES:
NA.32
MDL number:
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist


biological source

mouse

Quality Level

recombinant

expressed in NSO cells

assay

>95% (SDS-PAGE)

form

lyophilized powder

mol wt

55-60 kDa by SDS-PAGE (reducing), calculated mol wt 50 kDa

packaging

pkg of 50 μg

impurities

endotoxin, tested

UniProt accession no.

storage temp.

−20°C

Gene Information

mouse ... Nog(18121)

Biochem/physiol Actions

Binds and blocks the acitivity of bone morphogenetic proteins (BMPs).
Binds and blocks the acitivity of bone morphogenetic proteins (BMPs). Mature mouse noggin shares 99% and 83% sequence identity with human and Xenopus noggin, respectively.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to inhibit recombinant human BMP-4 induced alkaline phosphatase activity in ATDC5 cells.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

常规特殊物品

This item has



Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library



Noggin antagonism of BMP4 signaling controls development of the axial skeleton in the mouse.
Wijgerde M
Developmental Biology (2005)
TGF-beta superfamily members and ovarian follicle development.
Knight PG and Glister C
Reproduction (Cambridge, England) (2006)
The expression patterns of gremlin 1 and noggin in normal adult and tumor tissues.
Laurila R
International Journal of Clinical and Experimental Pathology (2013)



Global Trade Item Number

SKUGTIN
N6784-50UG04061834117704