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Merck
CN

N6879

α-Nicotinamide adenine dinucleotide, reduced disodium salt

≥90%

Synonym(s):

α-DPNH, α-Dihydrodiphosphopyridine nucleotide, α-Dihydronicotinamide adenine dinucleotide, α-NADH

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About This Item

Linear Formula:
C21H27N7O14P2Na2
CAS Number:
Molecular Weight:
709.40
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Form:
powder
Assay:
≥90%
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Quality Segment

assay

≥90%

form

powder

impurities

≤3% β-isomer

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@@H]([C@@H](O)[C@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20+,21+;;/m1../s1

InChI key

QRGNQKGQENGQSE-WPVKCSLBSA-L

Application

α-Nicotinamide adenine dinucleotide, reduced (α-NADH) may be used as a cosubstrate to assess the specificity and kinetics of NAD+/NADH and NADP+/NADPH dependent enzymes and to assess the dynamics of nucleotides in ion channels such as voltage-dependent mitochondrial ion channels (VDAC).

Other Notes

Analog of β-NADH, chemically reduced

Disclaimer

This is not the common NADH required in the usual enzyme systems.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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