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N7510

Nicardipine hydrochloride

≥98%, L-type voltage-dependent calcium channel blocker, powder

Synonym(s):

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-[methyl(phenylmethyl)amino]ethyl ester hydrochloride, YC-93

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About This Item

Empirical Formula (Hill Notation):
C26H29N3O6 · HCl
CAS Number:
54527-84-3
Molecular Weight:
515.99
NACRES:
NA.77
PubChem Substance ID:
24277856
UNSPSC Code:
12352200
EC Number:
259-198-4
MDL number:
MFCD00057327
Assay:
≥98%
Form:
powder
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Product Name

Nicardipine hydrochloride, powder, ≥98%

Quality Segment

100

assay

≥98%

form

powder

color

yellow

solubility

DMSO: ~1 mg/mL, 0.1 M NaOH: insoluble, H2O: slightly soluble, methanol: soluble

originator

EKR Therapeutics

storage temp.

2-8°C

SMILES string

Cl[H].COC(=O)C1=C(C)NC(C)=C(C1c2cccc(c2)[N+]([O-])=O)C(=O)OCCN(C)Cc3ccccc3

InChI

1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H

InChI key

AIKVCUNQWYTVTO-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Biochem/physiol Actions

Blocks L-type voltage-dependent calcium channels; antihypertensive.

Features and Benefits

This compound was developed by EKR Therapeutics. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

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