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Sigma-Aldrich

1-Naphthyl butyrate

esterase substrate

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Synonym(s):
Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester
Linear Formula:
CH3CH2CH2CO2C10H7
CAS Number:
3121-70-8
Molecular Weight:
214.26
Beilstein:
2558646
EC Number:
221-500-7
MDL number:
MFCD00003923
PubChem Substance ID:
24897845
NACRES:
NA.32

description

esterase substrate

Assay

≥99% (GC)

form

liquid

refractive index

n20/D 1.571 (lit.)

bp

125-130 °C/1 mmHg (lit.)

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

density

1.091 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CCCC(=O)Oc1cccc2ccccc12

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

InChI key

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

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Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Biochem/physiol Actions

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Substrates

Esterase substrate.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

143.6 °F - closed cup

Flash Point(C)

62 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Biochemical studies on sheep body louse Bovicola ovis (Schrank)(Phthiraptera: Trichodectidae): comparison of pyrethroid and organophosphate resistant and susceptible strains
Jazayeri AJ
Pesticide Biochemistry and Physiology, 80(1), 1-11 (2004)
J Yourno et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(6), 727-733 (1986-06-01)
Monocytes contain a characteristic, prominent set of membrane-bound nonspecific esterases with a slightly acid isoelectric point. These esterases are also detected at modest levels in some granulocyte preparations. They are not apparent in lymphocytes. Among 18 fresh myeloid leukemias and
P M Mattes et al.
Toxicology and applied pharmacology, 114(1), 71-76 (1992-05-01)
Carboxylesterase activity in the rat nasal mucosa plays an important role in the response of this tissue to certain toxic inhaled esters. We have examined this activity in extracts of both Fischer-344 rat and human nasal tissue using the substrate
Y Kaneko et al.
Blood, 60(2), 389-399 (1982-08-01)
We studied the karyotype in 26 children with ANLL, which was diagnosed on the basis of the FAB classification. Clonal chromosome abnormalities were found in 21 of 26 patients. Four patients, including 3 with Down's syndrome, had AML(M1). Nine patients
J Yourno et al.
Blood, 60(1), 24-29 (1982-07-01)
Lymphocytes from a case of B-cell chronic lymphocytic leukemia (CLL) were obtained in a highly purified state from a therapeutic leukapheresis preparation. The CLL lymphocytes showed a fine, scattered, granular pattern of nonspecific esterase cytochemical reactivity with either alpha-naphthyl acetate
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