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N8000

1-Naphthyl butyrate

Name: 1-Naphthyl butyrate
Brand: SIGMA

esterase substrate, ≥99% (GC), liquid

Synonym(s):

Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester

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About This Item

Linear Formula:

CH₃CH₂CH₂CO₂C₁₀H₇

CAS Number:

3121-70-8

Molecular Weight:

214.26

NACRES:

NA.32

PubChem Substance ID:

24897845

UNSPSC Code:

12352204

EC Number:

221-500-7

MDL number:

MFCD00003923

Beilstein/REAXYS Number:

2558646

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Product Name

1-Naphthyl butyrate, esterase substrate

Quality Level

200

assay

≥99% (GC)

form

liquid

refractive index

n20/D 1.571 (lit.)

bp

125-130 °C/1 mmHg (lit.)

solubility

ethanol: 100 mg/mL, clear, colorless to faintly yellow

density

1.091 g/mL at 20 °C (lit.)

storage temp.

−20°C

SMILES string

CCCC(=O)Oc1cccc2ccccc12

InChI

1S/C14H14O2/c1-2-6-14(15)16-13-10-5-8-11-7-3-4-9-12(11)13/h3-5,7-10H,2,6H2,1H3

InChI key

XIVJNRXPRQKFRZ-UHFFFAOYSA-N

General description

Esterase substrate.

Application

1-Naphthyl butyrate has been used as a substrate for esterase activity in sheep body louse Bovicola ovis and in chromogenic staining of flounder fish samples.

Biochem/physiol Actions

1-Naphthyl butyrate also called α-naphthyl butyrate is a substrate for esterase enzyme. α-naphthyl butyrate aids in assessing α-naphthyl butyrate esterase activity in monocytes and lymphocytes.

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

143.6 °F - closed cup

flash_point_c

62 °C - closed cup

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificates of Analysis (COA)

Lot/Batch Number

SLCM6290

0000430007

0000225467

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Nonspecific esterase of B lymphocytes from a case of chronic lymhocytic leukemia and of normal T lymphocytes: similar constellations of isoenzymes.

J Yourno et al.

Blood, 60(1), 24-29 (1982-07-01)

Lymphocytes from a case of B-cell chronic lymphocytic leukemia (CLL) were obtained in a highly purified state from a therapeutic leukapheresis preparation. The CLL lymphocytes showed a fine, scattered, granular pattern of nonspecific esterase cytochemical reactivity with either alpha-naphthyl acetate

Chromosome pattern in childhood acute nonlymphocytic leukemia (ANLL).

Y Kaneko et al.

Blood, 60(2), 389-399 (1982-08-01)

We studied the karyotype in 26 children with ANLL, which was diagnosed on the basis of the FAB classification. Clonal chromosome abnormalities were found in 21 of 26 patients. Four patients, including 3 with Down's syndrome, had AML(M1). Nine patients

alpha-Naphthyl butyrate carboxylesterase activity in human and rat nasal tissue.

P M Mattes et al.

Toxicology and applied pharmacology, 114(1), 71-76 (1992-05-01)

Carboxylesterase activity in the rat nasal mucosa plays an important role in the response of this tissue to certain toxic inhaled esters. We have examined this activity in extracts of both Fischer-344 rat and human nasal tissue using the substrate

Monocyte nonspecific esterase. Enzymologic characterization of a neutral serine esterase associated with myeloid cells.

J Yourno et al.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 34(6), 727-733 (1986-06-01)

Monocytes contain a characteristic, prominent set of membrane-bound nonspecific esterases with a slightly acid isoelectric point. These esterases are also detected at modest levels in some granulocyte preparations. They are not apparent in lymphocytes. Among 18 fresh myeloid leukemias and

Identification of alpha-naphthyl butyrate esterase as a plasma membrane ectoenzyme of monocytes and as a discrete intracellular membrane-bounded organelle in lymphocytes.

Bozdech MJ and Bainton DF

The Journal of Experimental Medicine, 153(1), 182-195 (1981)

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Global Trade Item Number

SKU	GTIN
N8000-10G	04061832918273
N8000-1G	04061834118305
N8000-250MG	04061834118312
N8000-5G	04061832918297

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