O2875
Orotic acid potassium salt
≥98%
Synonym(s):
6-Carboxy-2,4-dihydroxypyrimidine, Uracil-6-carboxylic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Linear Formula:
C5H3N2O4K
CAS Number:
Molecular Weight:
194.19
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
246-341-0
MDL number:
Assay:
≥98%
Form:
powder
Solubility:
1 M NaOH: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
Quality Segment
assay
≥98%
form
powder
solubility
1 M NaOH: 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES string
[K+].[O-]C(=O)C1=CC(=O)NC(=O)N1
InChI
1S/C5H4N2O4.K/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);/q;+1/p-1
InChI key
DHBUISJCVRMTAZ-UHFFFAOYSA-M
Application
Orotic acid (OA) is an intermediate in de novo pyrimidine biosynthesis that may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.