O5632
Linoleic acid, conjugated methyl ester
Synonym(s):
CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester
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About This Item
NACRES:
NA.25
UNSPSC Code:
12352211
biological source
plant (safflower)
assay
≥99% (GC)
form
liquid
technique(s)
GC/MS: suitable
HPLC: suitable
impurities
≤1% Linoleic acid methyl ester
functional group
carboxylic acid
ester
lipid type
omega FAs
shipped in
ambient
storage temp.
−20°C
Quality Level
Related Categories
Application
Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.
Biochem/physiol Actions
Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.
General description
Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.
Other Notes
A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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P G Toral et al.
Journal of dairy science, 101(7), 6109-6121 (2018-05-01)
A great deal of uncertainty still exists about intermediate metabolites and pathways explaining the biohydrogenation (BH) of 20- and 22-carbon polyunsaturated fatty acids (PUFA). Therefore, this study was conducted to provide further insight into the ruminal metabolism of 20:5 n-3
A D Martin et al.
Journal of dairy science, 98(8), 5374-5384 (2015-05-26)
To investigate the feasibility of milk fatty acids as predictors of onset of luteal activity (OLA), 87 lactations taken from 73 healthy Norwegian Red cattle were surveyed over 2 winter housing seasons. The feasibility of using frozen milk samples for
M Coppa et al.
Journal of dairy science, 102(11), 10483-10499 (2019-09-10)
The aims of this work were to determine the effect of upland origin on milk composition when comparing similar lowland and upland production system and to highlight the factors responsible for the added value of upland milk from commercial farms.
C Villot et al.
Animal : an international journal of animal bioscience, 14(2), 388-398 (2019-07-18)
High-starch diets (HSDs) fed to high-producing ruminants are often responsible for rumen dysfunction and could impair animal health and production. Feeding HSDs are often characterized by transient rumen pH depression, accurate monitoring of which requires costly or invasive methods. Numerous
Examination of the persistency of milk fatty acid composition responses to fish oil and sunflower oil in the diet of dairy cows
Shingfield KJ, et al.
Journal of Dairy Science, 89(2), 714-732 (2006)
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