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O6503

L-Ornithine monohydrochloride

Name: <SC>L</SC>-Ornithine monohydrochloride
Brand: SIGMA

BioReagent, suitable for cell culture, ≥99%

Synonym(s):

(S)-2,5-Diaminopentanoic acid monohydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₅H₁₂N₂O₂ · HCl

CAS Number:

3184-13-2

Molecular Weight:

168.62

UNSPSC Code:

12352209

NACRES:

NA.75

PubChem Substance ID:

24898036

EC Number:

221-678-6

Beilstein/REAXYS Number:

3625847

MDL number:

MFCD00064562

Biological source:

microbial

Form:

powder

Technique(s):

cell culture | mammalian: suitable

Assay:

≥99%

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Properties

biological source

microbial

Quality Segment

300

product line

BioReagent

assay

≥99%

form

powder

packaging

pkg of 100 g, pkg of 25 g

technique(s)

cell culture | mammalian: suitable

impurities

ammonia and citrulline, essentially free

solubility

H₂O: soluble 50 mg/mL, clear, colorless to very faintly yellow

SMILES string

Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1

InChI key

GGTYBZJRPHEQDG-WCCKRBBISA-N

Description

General description

L-Ornithine is the functional metabolite of L-arginine.

L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.

Application

L-Ornithine monohydrochloride has been used:

as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays
as a component in the standard medium for primary human hepatocytes (PHH) culture
as a creatine synthesis inhibitor

Biochem/physiol Actions

L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.

L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.

Other Notes

Product of arginine degradation by arginase

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Storage Class

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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