All Photos(3)

Documents

O6503

L-Ornithine monohydrochloride

Name: <SC>L</SC>-Ornithine monohydrochloride
Brand: SIGMA

BioReagent, suitable for cell culture, ≥99%

Sign Into View Organizational & Contract Pricing

All Photos(3)

Synonym(s):

(S)-2,5-Diaminopentanoic acid monohydrochloride

Empirical Formula (Hill Notation):

C₅H₁₂N₂O₂ · HCl

CAS Number:

3184-13-2

Molecular Weight:

168.62

Beilstein:

3625847

EC Number:

221-678-6

MDL number:

MFCD00064562

PubChem Substance ID:

24898036

NACRES:

NA.75

biological source

microbial

Quality Level

200

product line

BioReagent

Assay

≥99%

form

powder

packaging

pkg of 100 g
pkg of 25 g

technique(s)

cell culture | mammalian: suitable

impurities

ammonia and citrulline, essentially free

solubility

H₂O: soluble 50 mg/mL, clear, colorless to very faintly yellow

SMILES string

Cl.NCCC[C@H](N)C(O)=O

InChI

1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1

InChI key

GGTYBZJRPHEQDG-WCCKRBBISA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Attachment Factors

General description

L-Ornithine is the functional metabolite of L-arginine.

L-Ornithine is an amino acid that is not coded for by the genetic code. It is formed during the decomposition of argininine by arginase and participates in the urea cycle. Ornithine is the starting point for the formation of a family of polyamines that include spermine, spermidine and putrescine.

Application

L-Ornithine monohydrochloride has been used:

as a supplement in Dulbecco′s modified eagle medium (DMEM) for cell growth assays
as a component in the standard medium for primary human hepatocytes (PHH) culture
as a creatine synthesis inhibitor

Biochem/physiol Actions

L-ornithine acts as a precursor for polyamines. It may modulate the intake of food as an acute satiety signal in the neonatal chick brain.

L-Ornithine is used as a media supplement to support the biosynthesis of polyamines.

Other Notes

Product of arginine degradation by arginase

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

How to Find the Product Number

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503

Product Number

25G

Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

How to Find a Lot/Batch Number for COA

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').
For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').
For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

Ji L, et al.

Immunity, 51(2), 272-284 (2019)

Arginase 2 suppresses renal carcinoma progression via biosynthetic cofactor pyridoxal phosphate depletion and increased polyamine toxicity

Ochocki JD, et al.

Cell Metabolism, 27(6), 1263-1280 (2018)

Polyamines and their derivatives as modulators in growth and differentiation.

Z N Canellakis et al.

The Yale journal of biology and medicine, 62(5), 481-491 (1989-09-01)

The polyamines and their derivatives are essential for life in eukaryotic and most prokaryotic cells, but their exact role in preserving cell function is not clear. These polyamines provide endogenous cations and thus participate in regulation of the intracellular pH;

L-Ornithine is a potential acute satiety signal in the brain of neonatal chicks

Tran PV, et al.

Physiology & Behavior, 155, 141-148 (2016)

Arginine

Profiles of Drug Substances, Excipients, and Related Methodology, 27, 1-32 (2001)

View All Related Papers

Articles

L-Ornithine in Cell Culture

Discover L-ornithine, an important amino acid supplement, explore how L-ornithine is used in CHO and iPSC culture, and discover how poly-L-ornithine is used to enhance cell attachment.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service