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Merck
CN

O8010

Sigma-Aldrich

Okadaic acid ammonium salt

From plant (Prorocentrum concavum), ≥90% (HPLC), type 1 and type 2A protein phosphatases inhibitor, solid

Synonym(s):

OA

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About This Item

Empirical Formula (Hill Notation):
C44H68O13 · NH3
CAS Number:
155716-06-6
Molecular Weight:
822.03
MDL number:
MFCD00153856
UNSPSC Code:
12352106
PubChem Substance ID:
24898053
NACRES:
NA.77

Key Documents

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Product Name

Okadaic acid ammonium salt from Prorocentrum concavum, ≥90% (HPLC), solid

biological source

plant (Prorocentrum concavum)

Quality Level

200

Assay

≥90% (HPLC)

form

solid

color

white

solubility

H2O: 0.1 mg/mL
DMSO: soluble
ethanol: soluble

storage temp.

−20°C

SMILES string

[H][N+]([H])([H])[H].[H][C@]1(CC[C@@H](O)[C@@]2(O[C@@H](CC(C)=C2)C(C)\C=C\[C@@]3([H])CC[C@@]4(CCC5O[C@H]([C@@H](O)C[C@H](C)C6O[C@@]7(CCCCO7)CC[C@H]6C)C(=C)[C@@H](O)[C@]5([H])O4)O3)O1)C[C@@](C)(O)C([O-])=O

InChI

1S/C44H68O13.H3N/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);1H3/b10-9+;/t26-,27-,28+,30+,31+,32+,33?,34+,35-,36-,37?,38+,39-,41-,42+,43-,44-;/m1./s1

InChI key

ZBOMSHVRJSJGNR-JBNKPAQWSA-N

Related Categories

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.
Okadaic acid is a dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301 + H311 + H331,H315

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Regulatory Information

高风险级别生物产品--毒素类产品

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Certificates of Analysis (COA)

Lot/Batch Number
SLCN4651
SLCF6121
SLCD0695
SLCC9868
SLBZ9425

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