O9014
N-(3-Oxodecanoyl)-L-homoserine lactone
≥98% (TLC)
Synonym(s):
3-Oxo-N-[(3s)-2-Oxotetrahydrofuran-3-Yl]decanamide
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About This Item
Empirical Formula (Hill Notation):
C14H23NO4
Molecular Weight:
269.34
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
N-(3-Oxodecanoyl)-L-homoserine lactone,
assay
≥98% (TLC)
Quality Level
form
powder
color
white
application(s)
cell analysis
shipped in
wet ice
storage temp.
−20°C
SMILES string
CCCCCCCC(=O)CC(=O)N[C@H]1CCOC1=O
InChI
1S/C14H23NO4/c1-2-3-4-5-6-7-11(16)10-13(17)15-12-8-9-19-14(12)18/h12H,2-10H2,1H3,(H,15,17)/t12-/m0/s1
InChI key
KYGIKEQVUKTKRR-LBPRGKRZSA-N
General description
N-(3-oxodecanoyl) homoserine-L-lactone (3-oxo-C10 HSL) is among belongs to the group of homoserine lactones that includes N-octanoyl-homoserine lactone (N-C8-HSL), N-(3-oxododecanoyl)homoserine-L-lactone (3-oxo-C12-HSL), N-(3-Oxotetradecanoyl)-L-homoserine lactone (3-oxo-C14-HSL, N-(3-hydroxydecanoyl)-L-homoserine lactone, and N-(3-hydroxyoctanoyl)-L-homoserine lactone.
Application
N-(3-Oxodecanoyl)-L-homoserine lactone (3-Oxo-C10-HSL) may be used to study the signaling involved in the regulation of bacterial quorum sensing.
Biochem/physiol Actions
Acyl homoserine lactone used as an autoinducer of quorum signaling by Pseudomonas putida, Yersinia enterocolitica, and other Gram-negative bacteria.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Mair E A Churchill et al.
Methods in molecular biology (Clifton, N.J.), 692, 159-171 (2010-10-30)
Quorum sensing plays a central role in regulating many community-derived symbiotic and pathogenic relationships of bacteria, and as such has attracted much attention in recent years. Acyl-homoserine lactones (AHLs) are important signaling molecules in the quorum sensing gene-regulatory processes found
John F Teiber et al.
Methods in molecular biology (Clifton, N.J.), 692, 291-298 (2010-10-30)
Mammalian paraoxonases (PONs) are a unique, highly conserved family of calcium-dependent esterases consisting of PON1, PON2, and PON3. The PONs can hydrolyze the lactone ring of a range of N-acyl-L: -homoserine lactone (AHL) quorum sensing signaling molecules, rendering them inactive.
Bijay K Khajanchi et al.
Infection and immunity, 79(7), 2646-2657 (2011-05-04)
Aeromonas hydrophila leads to both intestinal and extraintestinal infections in animals and humans, and the underlying mechanisms leading to mortality are largely unknown. By using a septicemic mouse model of infection, we showed that animals challenged with A. hydrophila die
Global Trade Item Number
| SKU | GTIN |
|---|---|
| O9014-100MG | 04061834248774 |
| O9014-10MG | 04061832469102 |