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Merck
CN

P0100

Psilocybin

≥98% (HPLC), solid

Synonym(s):

3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl phosphate

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About This Item

Empirical Formula (Hill Notation):
C12H17N2O4P
CAS Number:
520-52-5
Molecular Weight:
284.25
UNSPSC Code:
12352200
NACRES:
NA.77
EC Number:
208-294-4
MDL number:
MFCD01310431

Key Documents

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SMILES string

CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12

assay

≥98% (HPLC)

form

solid

drug control

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada, kontrollierte Droge in Deutschland

solubility

H2O: >20 mg/mL

storage temp.

−20°C

Biochem/physiol Actions

Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic. It is the minor hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico. Psilocybin produces muscle relaxation, dilation of pupils, vivid visual and auditory distortions, and emotional disturbances.
Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
127K4703

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Matthew W Johnson et al.
Drug and alcohol dependence, 123(1-3), 132-140 (2011-12-02)
Psilocybin is a well-characterized classic hallucinogen (psychedelic) with a long history of religious use by indigenous cultures, and nonmedical use in modern societies. Although psilocybin is structurally related to migraine medications, and case studies suggest that psilocybin may be efficacious
Michael Kometer et al.
Biological psychiatry, 72(11), 898-906 (2012-05-15)
Serotonin (5-HT) 1A and 2A receptors have been associated with dysfunctional emotional processing biases in mood disorders. These receptors further predominantly mediate the subjective and behavioral effects of psilocybin and might be important for its recently suggested antidepressive effects. However
Robin L Carhart-Harris et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2138-2143 (2012-02-07)
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found
Hallucinogen actions on human brain revealed.
Hyeong-Min Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 1820-1821 (2012-02-07)
Opening doors of perception: psychedelic drugs and end-of-life care.
Norra Macready
Journal of the National Cancer Institute, 104(21), 1619-1620 (2012-10-30)
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