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Merck
CN

P0369

Anti-Peroxisome Proliferator Activated Receptor α antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-PPARα

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
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Product Name

Anti-Peroxisome Proliferator Activated Receptor α antibody produced in rabbit, ~1 mg/mL, affinity isolated antibody, buffered aqueous solution

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 52 kDa

species reactivity

mouse

concentration

~1 mg/mL

technique(s)

direct immunofluorescence: 1:100
immunoprecipitation (IP): suitable
western blot: 1 μg/mL

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... PPARA(5465)
mouse ... Ppara(19013)

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

synthetic peptide corresponding to residues M(1)VDTESPICPLSPLEADD(18)C of mouse PPARα. The human sequence is 95% (17/18 amino acids) homologous.

Physical form

Solution in phosphate buffered saline containing 1 mg/ml bovine serum albumin and 0.05% sodium azide.

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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Carmen De Caro et al.
Frontiers in pharmacology, 11, 620221-620221 (2021-02-19)
Pain conditions, such as neuropathic pain (NP) and persistent inflammatory pain are therapeutically difficult to manage. Previous studies have shown the involvement of glutamate receptor in pain modulation and in particular same of these showed the key role of the
Claudia Cristiano et al.
Brain, behavior, and immunity, 74, 166-175 (2018-09-09)
Autism spectrum disorders (ASD) are a group of heterogeneous neurodevelopmental conditions characterized by impaired social interaction, and repetitive stereotyped behaviours. Interestingly, functional and inflammatory gastrointestinal diseases are often reported as a comorbidity in ASDs, indicating gut-brain axis as a novel
Maria Bove et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 149, 112820-112820 (2022-03-16)
Drug-naïve psychotic patients show metabolic and hepatic dysfunctions. The rat social isolation model of psychosis allows to investigate mechanisms leading to these disturbances to which oxidative stress crucially contributes. Here, we investigated isolation-induced central and peripheral dysfunctions in glucose homeostasis
Giuseppe D'Agostino et al.
Molecular metabolism, 4(7), 528-536 (2015-07-03)
Nuclear peroxisome proliferator activated receptor-α (PPAR-α) plays a fundamental role in the regulation of lipid homeostasis and is the target of medications used to treat dyslipidemia. However, little is known about the role of PPAR-α in mouse behavior. To investigate
T Pulinilkunnil et al.
International journal of obesity (2005), 38(2), 205-215 (2013-07-03)
Although obesity increases the risk of developing cardiomyopathy, the mechanisms underlying the development of this cardiomyopathy are incompletely understood. As obesity is also associated with increased intramyocardial triacylglycerol (TAG) deposition, also referred to as cardiac steatosis, we hypothesized that alterations

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