P0689
(R)-(+)-Propranolol hydrochloride
≥98% (TLC), Beta-adrenergic antagonist
Synonym(s):
Propranolol HCl, (R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride
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About This Item
Linear Formula:
C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl
CAS Number:
Molecular Weight:
295.80
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
235-961-7
MDL number:
Beilstein/REAXYS Number:
5780490
Assay:
≥98% (TLC)
Product Name
(R)-(+)-Propranolol hydrochloride, ≥98% (TLC)
Quality Segment
assay
≥98% (TLC)
mp
196-198 °C (lit.)
solubility
ethanol: 10 mg/mL, DMSO: <14.5 mg/mL, H2O: 50 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL
originator
AstraZeneca
storage temp.
2-8°C
SMILES string
Cl.CC(C)NC[C@@H](O)COc1cccc2ccccc12
InChI
1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1
InChI key
ZMRUPTIKESYGQW-PFEQFJNWSA-N
General description
With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.
Biochem/physiol Actions
Less active enantiomer of propranolol.
Features and Benefits
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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