Skip to Content
Merck
CN

Key Documents

View All Documentation

P0689

(R)-(+)-Propranolol hydrochloride

≥98% (TLC), Beta-adrenergic antagonist

Synonym(s):

Propranolol HCl, (R)-1-(isopropylamino)-3-(1-naphthyloxy)-2-propanol hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
C10H7OCH2CH(OH)CH2NHCH(CH3)2·HCl
CAS Number:
13071-11-9
Molecular Weight:
295.80
NACRES:
NA.77
PubChem Substance ID:
24898124
UNSPSC Code:
12352200
EC Number:
235-961-7
MDL number:
MFCD00064546
Beilstein/REAXYS Number:
5780490
Assay:
≥98% (TLC)
Quality level:
200
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

(R)-(+)-Propranolol hydrochloride, ≥98% (TLC)

Quality Level

200

assay

≥98% (TLC)

mp

196-198 °C (lit.)

solubility

ethanol: 10 mg/mL, DMSO: <14.5 mg/mL, H2O: 50 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 8.0 mg/mL

originator

AstraZeneca

storage temp.

2-8°C

SMILES string

Cl.CC(C)NC[C@@H](O)COc1cccc2ccccc12

InChI

1S/C16H21NO2.ClH/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16;/h3-9,12,14,17-18H,10-11H2,1-2H3;1H/t14-;/m1./s1

InChI key

ZMRUPTIKESYGQW-PFEQFJNWSA-N

Related Categories

General description

With heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.

Biochem/physiol Actions

Less active enantiomer of propranolol.

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000490676
0000490676
0000476091
0000476091
0000363295

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Montserrat Solé et al.
Analytical and bioanalytical chemistry, 396(2), 649-656 (2009-10-20)
Environmental risk assessments of human pharmaceuticals and other 'emerging contaminants' should integrate both population-relevant endpoints and biomarkers of potential modes of action in a range of species. Adult Mytilus galloprovincialis were exposed to the beta-adrenergic receptor blocker propranolol or to
Jieyu Xu et al.
Toxicology in vitro : an international journal published in association with BIBRA, 48, 286-301 (2018-02-07)
Immortalized liver cells have been used for evaluating the toxicity of compounds; however, excessive glutathione is considered to lessen cytotoxicity. In this study, we compared the effects of glutathione depletion on cytotoxicities of drugs using HepaRG and HepG2 cells, which
Silvia Gramolelli et al.
Cancer research, 80(15), 3116-3129 (2020-06-11)
Kaposi sarcoma is a tumor caused by Kaposi sarcoma herpesvirus (KSHV) infection and is thought to originate from lymphatic endothelial cells (LEC). While KSHV establishes latency in virtually all susceptible cell types, LECs support spontaneous expression of oncogenic lytic genes

Global Trade Item Number

SKUGTIN
P0689-100MG04061834353010
P0689-500MG04061832092478

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service