Skip to Content
Merck
CN

Key Documents

View All Documentation

P0865

N-(3-Pyridyl)indomethacinamide

≥98%

Synonym(s):

N-(3-Pyridyl)-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetamide, N-3PyIA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C24H20N3O3Cl
CAS Number:
261766-29-4
Molecular Weight:
433.89
NACRES:
NA.77
PubChem Substance ID:
329820062
UNSPSC Code:
12352200
MDL number:
MFCD02683393
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Segment

200

assay

≥98%

form

powder

solubility

chloroform: 10 mg/mL to clear, colorless to light yellow

shipped in

wet ice

storage temp.

−20°C

SMILES string

COc1ccc2n(c(C)c(CC(=O)Nc3cccnc3)c2c1)C(=O)c4ccc(Cl)cc4

InChI

1S/C24H20ClN3O3/c1-15-20(13-23(29)27-18-4-3-11-26-14-18)21-12-19(31-2)9-10-22(21)28(15)24(30)16-5-7-17(25)8-6-16/h3-12,14H,13H2,1-2H3,(H,27,29)

InChI key

DTAPHQYAZUTCIG-UHFFFAOYSA-N

Biochem/physiol Actions

Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor (IC50 = 0.1 μM, human recombinant); about 300-fold less potent as an inhibitor of human recombinant COX-1. Not as selective with natural ovine COX (IC50 = 75 μM for COX-1 and 50 μM for COX-2).
Potent and selective reversible cyclooxygenase-2 (COX-2) inhibitor. Not as selective with natural ovine COX.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library