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Merck
CN

P1060

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium salt

~95%

Synonym(s):

L-α-Phosphatidyl-L-serine, dioleoyl sodium salt

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About This Item

Linear Formula:
C42H77NO10PNa
CAS Number:
70614-14-1
Molecular Weight:
810.03
NACRES:
NA.25
PubChem Substance ID:
24898148
UNSPSC Code:
51191904
MDL number:
MFCD00133436

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InChI

1S/C42H78NO10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,38-39H,3-16,21-37,43H2,1-2H3,(H,46,47)(H,48,49)/b19-17-,20-18-/t38-,39-/m0/s1

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI key

WTBFLCSPLLEDEM-MDZJKYSESA-N

biological source

synthetic (organic)

assay

~95%

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCH3206
071M1664V
120M1762V
120M1762
018K1398

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Xiaoyang Qi et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(18), 5840-5851 (2009-09-10)
Saposin C is a multifunctional protein known to activate lysosomal enzymes and induce membrane fusion in an acidic environment. Excessive accumulation of lipid-coupled saposin C in lysosomes is cytotoxic. Because neoplasms generate an acidic microenvironment, caused by leakage of lysosomal
Angelica Wikström et al.
The journal of physical chemistry. B, 112(44), 14069-14074 (2008-10-15)
The lipid exchange/transfer between lipid membranes is important for many biological functions. To learn more about how the dynamics of such processes can be studied, we have investigated the interaction of positively and negatively charged lipid vesicles with supported lipid
Kim S Horger et al.
Journal of the American Chemical Society, 131(5), 1810-1819 (2009-01-22)
This paper describes a method to form giant liposomes in solutions of physiologic ionic strength, such as phosphate buffered saline (PBS) or 150 mM KCl. Formation of these cell-sized liposomes proceeded from hybrid films of partially dried agarose and lipids.
Charles H Davis et al.
Biophysical journal, 96(3), 785-797 (2009-02-03)
The amyloid-beta (Abeta) peptide is a key aggregate species in Alzheimer's disease. Although important aspects of Abeta peptide aggregation are understood, the initial stage of aggregation from monomer to oligomer is still not clear. One potential mediator of this early
M Klacsová et al.
Biochimica et biophysica acta, 1808(9), 2136-2146 (2011-05-11)
Small-angle neutron scattering and coarse-grained molecular dynamics simulations have been used to determine the structural parameters (bilayer thickness D, polar region thickness D(H), interfacial lateral area of the unit cell A(UC) and alcohol partial interfacial area A(CnOH)) of fluid dioleoylphosphatidylcholine:dioleoylphosphatidylserine
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