About This Item
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL, clear
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 40 mg/mL
SMILES string
O.CC(N\C(Nc1ccncc1)=N\C#N)C(C)(C)C
InChI
1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2
InChI key
AFJCNBBHEVLGCZ-UHFFFAOYSA-N
Gene Information
human ... ABCC9(10060), KCNJ11(3767)
mouse ... Kcnj11(16514)
rat ... Kcna1(24520), Kcnj1(24521), Kcnj11(83535), Kcnj5(29713), Kcnj8(25472)
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Application
- in repolarization studies by infusing into left anterior descending artery (LAD)
- to induce ATP-sensitive K+ (KATP) current in ventricular myocytes for electrophysiological studies
- as a KATP opener to treat myocardial cells
Biochem/physiol Actions
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
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