P1761
trans-2-Phenylcyclopropylamine hemisulfate salt
Synonym(s):
Tranylcypromine
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About This Item
Linear Formula:
C9H11N · 1/2H2SO4
CAS Number:
Molecular Weight:
182.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
236-807-1
MDL number:
assay
≥98% (perchloric acid titration)
Quality Segment
form
powder
solubility
water: 0.0333 g/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.N[C@H]1C[C@@H]1c2ccccc2.N[C@H]3C[C@@H]3c4ccccc4
InChI
1S/2C9H11N.H2O4S/c2*10-9-6-8(9)7-4-2-1-3-5-7;1-5(2,3)4/h2*1-5,8-9H,6,10H2;(H2,1,2,3,4)/t2*8-,9+;/m11./s1
InChI key
BKPRVQDIOGQWTG-KAVFMPKWSA-N
Biochem/physiol Actions
trans-2-Phenylcyclopropylamine acts as an inhibitor of lysine-specific demethylase 1 (LSD1). It exhibits anti-depressant and anxiolytic activity. Tranylcypromine shows therapeutic effects against mood and anxiety issues. It also exhibits anti-osteoclastogenic effects through monoamine oxidase-A (MAO-A). Tranylcypromine may play a role in bone remodeling in mice.
Non-selective MAO-A/B inhibitor.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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