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P1868

Protein Phosphatase 2A2 from bovine kidney

buffered aqueous glycerol solution

Synonym(s):

PP2A2

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About This Item

NACRES:
NA.54
UNSPSC Code:
12352204
Specific activity:
~2.0 U/vial
Biological source:
bovine kidney
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biological source

bovine kidney

Quality Segment

200

form

buffered aqueous glycerol solution

specific activity

~2.0 U/vial

mol wt

dimer 101 kDa (65 kDa and 36 kDa)

shipped in

dry ice

storage temp.

−70°C

General description

Protein phosphatase 2A (PP2A) is a specific protamine-kinase-inactivating phosphatase, one common physiological form of which is PP2A2.

Application

Protein phosphatase 2A2 has been used in a study to investigate two heat-stable protein inhibitors. It has also been used in a study to describe the purification and properties of a protamine kinase from bovine kidney microsomes.

Biochem/physiol Actions

Protein Phosphatase 2A2 from bovine kidney was shown to be a unique inhibitor of protamine kinase while other phosphatases in the same family including PP1, PP2B, PP2C did not show any inhibition.

Physical form

Solution of 1 μg per vial in 50 μl of 50 mM Tris-HCl, pH 7.0, containing 14 mM β-Mercaptoethanol, 1mM benzamidine, 0.1 mM PMSF, 1mM EDTA, and 50% glycerol.

Other Notes

One unit will release 1 nanomole of inorganic phosphate from (32)P-labeled phosphorylase per minute at pH 7.0 at 30 deg C.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H317

Hazard Classifications

Skin Sens. 1

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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