P2110
Anti-Platelet-Derived Growth Factor Receptor α antibody produced in goat
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-PDGF Rα
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (d), IHC (p), Neutral, WB
Citations:
5
biological source
goat
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human
technique(s)
direct ELISA: 0.5-1.0 μg/mL, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 15 μg/mL using human tissue sections, neutralization: suitable, western blot: 0.1-0.2 μg/mL
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... PDGFRA(5156)
General description
Blocks cell surface human or mouse PDGF Receptor α mediated biological activity induced by PDGF-AA.
Immunogen
recombinant soluble human platelet-derived growth factor receptor α expressed in Sf 21 cells.
Biochem/physiol Actions
Platelet-derived growth factor (PDGF) is a serum growth factor purified from human platelets. The cellular effects of PDGF are mediated by binding to PDGF α- and PDGF β-receptors which leads to activation of downstream signaling via PI3K, STAT and Ras/MAPK. PDGFR stimulates the proliferation of cells of connective tissue and glial cells, survival, differentiation, chemotaxis and wound healing.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
13 - Non Combustible Solids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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