P2172
C-Phycocyanin from Spirulina sp.
lyophilized powder
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About This Item
Form:
lyophilized powder
Biological source:
Spirulina
Product Name
C-Phycocyanin from Spirulina sp., lyophilized powder
biological source
Spirulina
form
lyophilized powder
composition
Protein, ~40% Lowry
concentration
30-50% protein (Lowry)
storage temp.
2-8°C
Quality Level
Gene Information
Spirulina ... cpcA(41380954), cpcB(41380955)
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Application
C-Phycocyanin from Spirulina sp. has been used:
- as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
- as a standard to confirm the antibacterial activity
- to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
- to identify the phycocyanin from water extracted Spirulina maxima sample
Biochem/physiol Actions
C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria.
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.
General description
C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.
Packaging
Package size based on protein content
Physical form
Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Jun-Ichi Ishihara et al.
Biochemistry and biophysics reports, 34, 101469-101469 (2023-05-01)
The one-dimensional multicellular cyanobacterium, Anabaena sp. PCC 7120, exhibits a simple topology consisting of two types of cells under the nitrogen-depleted conditions. Although the differentiated (heterocyst) and undifferentiated cells (vegetative cells) were distinguished by their cellular shapes, we found that
C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro
Bhat VB and Madyastha KM
Biochemical and biophysical research communications, 275(1), 20-25 (2000)
C-Phycocyanin from Spirulina Inhibits ?-Synuclein and Amyloid ?-Fibril Formation but Not Amorphous Aggregation
Liu Y, et al.
Journal of Natural Products, 82(1), 66-73 (2019)
Evaluating fluorescence spectroscopy as a tool to characterize cyanobacteria intracellular organic matter upon simulated release and oxidation in natural water
Korak JA, et al.
Water Research, 68(1), 432-443 (2015)
Bing Li et al.
Biotechnology and applied biochemistry, 43(Pt 3), 155-164 (2005-12-01)
C-phycocyanin (C-PC), a water-soluble protein pigment, isolated from Spirulina platensis, is of great importance because of its various medical and pharmacological properties. In the present study, we first investigated the effect of highly purified C-PC on growth and proliferation of
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