P2172
C-Phycocyanin from Spirulina sp.
lyophilized powder
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About This Item
Form:
lyophilized powder
Biological source:
Spirulina
biological source
Spirulina
form
lyophilized powder
composition
Protein, ~40% Lowry
concentration
30-50% protein (Lowry)
storage temp.
2-8°C
Quality Level
Gene Information
Spirulina ... cpcA(41380954), cpcB(41380955)
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General description
C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.
Application
C-Phycocyanin from Spirulina sp. has been used:
- as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
- as a standard to confirm the antibacterial activity
- to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
- to identify the phycocyanin from water extracted Spirulina maxima sample
Biochem/physiol Actions
C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria.
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.
Packaging
Package size based on protein content
Physical form
Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
动植物源性产品
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Bing Li et al.
Biotechnology and applied biochemistry, 43(Pt 3), 155-164 (2005-12-01)
C-phycocyanin (C-PC), a water-soluble protein pigment, isolated from Spirulina platensis, is of great importance because of its various medical and pharmacological properties. In the present study, we first investigated the effect of highly purified C-PC on growth and proliferation of
Screening of anti-bacterial activity of C-phycocyanin and its minimum inhibitory concentration (MIC) determination by agar dilution method
Murugan T and Madhavan R
Asian Journal of Biological Sciences, 6(1), 41-45 (2011)
Evaluating fluorescence spectroscopy as a tool to characterize cyanobacteria intracellular organic matter upon simulated release and oxidation in natural water
Korak JA, et al.
Water Research, 68(1), 432-443 (2015)
Protective effect of water extracted Spirulina maxima on glutamate-induced neuronal cell death in mouse hippocampal HT22 cell
Lee HY, et al.
Pharmacognosy magazine, 14(54), 242-242 (2018)
C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro
Bhat VB and Madyastha KM
Biochemical and biophysical research communications, 275(1), 20-25 (2000)
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