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Merck
CN

P2186

Sigma-Aldrich

[pGlu4]-Myelin basic protein fragment 4-14

≥97% (HPLC)

Synonym(s):

pGlu-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu

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About This Item

Empirical Formula (Hill Notation):
C60H100N20O17
CAS Number:
136132-68-8
Molecular Weight:
1373.56
MDL number:
MFCD00133754
UNSPSC Code:
12352200
PubChem Substance ID:
24898284

Key Documents

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Assay

≥97% (HPLC)

form

powder

solubility

water: 5 mg/mL, clear, colorless

UniProt accession no.

P04370

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C(CCCNC(N)=N)NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C(CCCNC(N)=N)NC(=O)C(CCCCN)NC(=O)C3CCC(=O)N3)C(O)=O

InChI

1S/C60H100N20O17/c1-32(2)28-42(58(96)97)77-53(91)41(29-33-15-17-34(83)18-16-33)76-49(87)36(11-4-6-24-62)73-54(92)43(30-81)78-50(88)37(12-7-25-68-59(64)65)72-52(90)39(19-21-46(63)84)74-55(93)44(31-82)79-56(94)45-14-9-27-80(45)57(95)40(13-8-26-69-60(66)67)75-48(86)35(10-3-5-23-61)71-51(89)38-20-22-47(85)70-38/h15-18,32,35-45,81-83H,3-14,19-31,61-62H2,1-2H3,(H2,63,84)(H,70,85)(H,71,89)(H,72,90)(H,73,92)(H,74,93)(H,75,86)(H,76,87)(H,77,91)(H,78,88)(H,79,94)(H,96,97)(H4,64,65,68)(H4,66,67,69)

InChI key

RCRPGVVPXJBQFQ-UHFFFAOYSA-N

Gene Information

mouse ... Mbp(17196)

Amino Acid Sequence

Glp-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu

General description

Specific substrate for protein kinase C

Biochem/physiol Actions

Specific substrate for protein kinase C.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
041M1588V
031M1569V
090M1417
040M1631
129K1300

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I Yasuda et al.
Biochemical and biophysical research communications, 166(3), 1220-1227 (1990-02-14)
Among various phosphate acceptor proteins and peptides so far tested, a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, Gln-Lys-Arg-Pro-Ser(8)-Gln-Arg-Ser-Lys-Tyr-Leu, (MBP4-14), is the most specific and convenient substrate which can be used for selective assay of protein

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