P222
Pandinotoxin-Kα
>99%, powder
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About This Item
Empirical Formula (Hill Notation):
C169H267N53O48S7
CAS Number:
Molecular Weight:
4033.71
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:
assay
>99%
form
powder
color
off-white
storage temp.
−20°C
General description
Pandinotoxin (PiTX)-Kα is a 35 amino acid peptide isolated from venom of the scorpion Pandinus imperaton. PiTX-Kβ and PiTXγ are other two members of pandinotoxin group. All the three pandinotoxins have structures similar to another scorpion toxin charybdotoxin (ChTX). The structure of PiTXs contains a β-sheet at the C- terminal end with three cysteines which is linked to the central α-helix by two disulfide bridges (C17-C35 and C13-C33) and to an extended amino-terminal fragment by the third disulfide bridge (C7-C28).
Biochem/physiol Actions
Pandinotoxin (PiTX) –Kα along with PiTX-Kβ and PiTXγ plays a vital role in blocking voltage-gated K+ channels.
Legal Information
Sold with the permission of University of Maryland.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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