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Merck
CN

P2959

PD 142,893

≥97% (HPLC)

Synonym(s):

N-Acetyl-β-Phenyl-D-Phe-Leu-Asp-Ile-Ile-Trp

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About This Item

Empirical Formula (Hill Notation):
C50H65N7O10
CAS Number:
Molecular Weight:
924.09
UNSPSC Code:
12352200
MDL number:
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assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](NC(C)=O)C(c1ccccc1)c2ccccc2)[C@@H](C)CC)C(=O)N[C@@H](Cc3c[nH]c4ccccc34)C(O)=O

General description

Contains the conserved endothelin sequence, His-Leu-Asp-Ile-Ile-Trp, with His replaced by a bulky aromatic moiety.

Biochem/physiol Actions

Non-selective endothelin receptor antagonist.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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