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P3496

(+/-)-8-Prenylnaringenin

Name: (+/-)-8-Prenylnaringenin
Brand: SIGMA

EGF signaling inhibitor, powder

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₂₀O₅

Molecular Weight:

340.37

UNSPSC Code:

12352200

PubChem Substance ID:

329820176

NACRES:

NA.56

MDL number:

MFCD00272175

Form:

powder

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Properties

Product Name

(+/-)-8-Prenylnaringenin, Plant-derived estrogen receptor ligand

form

powder

storage temp.

−20°C

SMILES string

C\C(C)=C\Cc1c(O)cc(O)c2C(=O)CC(Oc12)c3ccc(O)cc3

InChI

1S/C20H20O5/c1-11(2)3-8-14-15(22)9-16(23)19-17(24)10-18(25-20(14)19)12-4-6-13(21)7-5-12/h3-7,9,18,21-23H,8,10H2,1-2H3

InChI key

LPEPZZAVFJPLNZ-UHFFFAOYSA-N

Description

Biochem/physiol Actions

8-Prenylnaringenin, a strong plant-derived estrogen receptor ligand, is a phytoestrogen that inhibits multidrug resistance-associated transporters, P-glycoprotein and MRP1. 8-Prenylnaringenin also inhibits EGF signaling at the level of phosphatidylinositol-3-OH kinase ((PI(3)K))activity.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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