P3892
Poly-L -arginine hydrochloride
suitable for bioconjugations, Mol wt >70,000
Synonym(s):
L-Arginine homopolymer hydrochloride
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About This Item
CAS Number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
Poly-
form
powder or solid
Quality Segment
mol wt
>70,000
technique(s)
bioconjugation: suitable
color
white to off-white
storage temp.
−20°C
SMILES string
Cl.NC(CCCNC(N)=N)C(O)=O
InChI
1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1
InChI key
PQEISBBDIRAKGR-LFELFHSZSA-N
Application
Poly-L -arginine hydrochloride has been used:
- as polyelectrolyte solution in the synthesis of biodegradable capsules
- as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells
- in assay for the determination of binding activity of C-reactive protein for polycationic ligands
Biochem/physiol Actions
Poly-L -arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent.
Analysis Note
Contains 3% or less ornithine residue by TLC.
Molecular weight based on viscosity of precursor poly-L -ornithine.
Other Notes
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
PPE (personal protective equipment)
Eyeshields, Gloves, type N95 (US)
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