P3905
pGlu-His-Pro
≥97% (TLC)
Synonym(s):
TRH, Thyrotropin releasing hormone
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About This Item
Empirical Formula (Hill Notation):
C16H21N5O5
CAS Number:
Molecular Weight:
363.37
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥97% (TLC)
storage temp.
−20°C
SMILES string
OC(=O)C1CCCN1C(=O)C(Cc2cnc[nH]2)NC(=O)C3CCC(=O)N3
Gene Information
mouse ... Trhr(22045)
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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L O Koskinen
British journal of pharmacology, 87(3), 509-519 (1986-03-01)
Local cerebral and peripheral blood flow in conscious and anaesthetized rabbits were investigated with the microsphere method, before and after the i.v. administration of 25 or 50 micrograms kg-1 thyrotropin-releasing hormone (TRH). Before the experiment, the cervical sympathetic chain was
E R Spindel et al.
Brain research, 216(2), 343-350 (1981-07-20)
Thyrotropin-releasing hormone (TRH) injected into the lateral ventricle of the rat's brain was rapidly metabolized to deamido-TRH (DA-TRH). Brain levels of TRH decreased with a half-life of 7 min, while the DA-TRH formed from its disappeared with a half-life of
P Salers
Regulatory peptides, 50(2), 101-111 (1994-02-24)
The effect of streptozotocin (STZ)-induced diabetes on the concentrations of deamidated TRH (TRH-OH), a metabolite of thyrotropin-releasing hormone (TRH) and prolyl endopeptidase (PE) activity were studied in the pancreas of neonatal rats to determine the contribution of beta-cells to PE
V Strbák et al.
Endocrine regulations, 25(1-2), 134-138 (1991-06-01)
Hypothalamic hormones represent a peculiar group of hormones present in milk in surprisingly high concentrations. High levels of these neuropeptides raised the question of their origin. The hypothesis suggesting local synthesis of TRH in the mammary gland was, therefore, tested.
Y Kagabu et al.
General and comparative endocrinology, 111(3), 395-403 (1998-08-26)
The effects of thyrotropin-releasing hormone (TRH) and its metabolites, cyclo(His-Pro) and TRH-OH, on growth hormone (GH) and prolactin (PRL) synthesis were investigated using primary cultured pituitary cells of the common carp, Cyprinus carpio. The effects of these pep tides on
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