Key Documents

View All Documentation

P4365

PJ-34 hydrochloride hydrate

Name: PJ-34 hydrochloride hydrate
Brand: SIGMA

≥98% (HPLC), powder

Synonym(s):

PARP Inhibitor VIII, PJ 34 HCl, N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-(N,N-dimethylamino)acetamide hydrochloride

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₇N₃O₂ · HCl · xH₂O

CAS Number:

344458-15-7

Molecular Weight:

331.80 (anhydrous basis)

UNSPSC Code:

12352200

PubChem Substance ID:

24898531

NACRES:

NA.77

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to yellow

solubility

H₂O: 22 mg/mL

SMILES string

Cl[H].[H]O[H].CN(C)CC(=O)Nc1ccc2NC(=O)c3ccccc3-c2c1

InChI

1S/C17H17N3O2.ClH.H2O/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15;;/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22);1H;1H2

InChI key

YCALIZUKAFUQCH-UHFFFAOYSA-N

Description

Application

PJ-34 hydrochloride hydrate has been used:

as a poly(ADP-ribose) polymerase (PARP) inhibitor 1 in rats to test the effect of PAPR1 in neuropathic pain
as a component of protein extraction buffer to enable visualization of the high-molecular-weight smear of PARylated proteins in various cell samples
as PARP inhibitor in murine MLE-12 epithelial cell line

Biochem/physiol Actions

PJ-34 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor.

PJ-34 is a prototypic poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
P4365-5MG	04061834374428