P4380
Protamine sulfate
powder
Synonym(s):
Salmine, Salmine from salmon
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About This Item
Product Name
Protamine sulfate salt from salmon, Grade II
biological source
fish (salmon)
Quality Segment
type
Grade II
form
powder
color
white to off-white
solubility
6 M HCl: 25 mg/mL, clear, colorless to light yellow
General description
Protamine sulfate (PS), a polycationic, positively charged protein is mostly made up of poly(l-arginine). It is obtained from salmon sperm protein.
Application
Protamine sulfate salt from salmon has been used in the generation of protamine silica nanocomposites.
May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Biochem/physiol Actions
Protamine sulfate is highly preferred in cardiovascular surgical procedures to reverse the anticoagulant properties of heparin. It is used for biomedical and biotechnological applications due to its biodegradablity.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.
Analysis Note
May contain insolubles as well as histones.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
低风险生物材料
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P4380-25G | 04061834374435 |
| P4380-100G | 04061832948430 |