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P4886

Poly-L-glutamic acid sodium salt

mol wt 50,000-100,000

Sustainability features

Synonym(s):

L-Glutamic acid homopolymer sodium salt

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About This Item

CAS Number:
26247-79-0
UNSPSC Code:
12352209
NACRES:
NA.25
MDL number:
MFCD00081868
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form

powder

Quality Segment

mol wt

50,000-100,000

greener alternative product score

old score: 46
new score: 43
Find out more about DOZN™ Scoring

sustainability

Sustainability features

color

white to off-white

application(s)

detection

greener alternative category

storage temp.

−20°C

SMILES string

N([C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)[C@@H](N)CCC(=O)O

InChI

1S/C15H23N3O10/c16-7(1-4-10(19)20)13(25)17-8(2-5-11(21)22)14(26)18-9(15(27)28)3-6-12(23)24/h7-9H,1-6,16H2,(H,17,25)(H,18,26)(H,19,20)(H,21,22)(H,23,24)(H,27,28)/t7-,8-,9-/m0/s1

InChI key

BUZMZDDKFCSKOT-CIUDSAMLSA-N

General description

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Designing Safer Chemicals”, "Safer Solvents and Auxiliaries" and “Design for Energy Efficiency”. Click here to view its DOZN scorecard.

Application


  • A real-time fluorescence assay for protease activity and inhibitor screening based on the aggregation-caused quenching of a perylene probe.: Demonstrates the utility of Poly-L-glutamic acid sodium salt in developing sensitive fluorescence assays for enzyme activity, which could streamline the development of new therapeutic inhibitors (Wang Y et al., 2018).

  • Interfacial and structural characteristics of polyelectrolyte multilayers used as cushions for supported lipid bilayers.: Explores the role of Poly-L-glutamic acid sodium salt in stabilizing lipid bilayers, crucial for bio-mimetic systems and drug delivery applications (Wlodek M et al., 2017).

  • The interaction of clozapine loaded nanocapsules with the hCMEC/D3 cells - In vitro model of blood brain barrier.: Highlights the use of Poly-L-glutamic acid sodium salt for drug encapsulation, enhancing the delivery of therapeutic agents across the blood-brain barrier (Łukasiewicz S et al., 2017).

  • A Chimeric LysK-Lysostaphin Fusion Enzyme Lysing Staphylococcus aureus Cells: a Study of Both Kinetics of Inactivation and Specifics of Interaction with Anionic Polymers.: Investigates the synergistic effects of Poly-L-glutamic acid sodium salt in enhancing the antimicrobial properties of bio-engineered enzymes, presenting a novel approach to combat bacterial infections (Filatova LY et al., 2016).

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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