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Merck
CN

P5022

Pamoic acid disodium salt

Synonym(s):

4,4′-Methylenebis(3-hydroxy-2-naphthoic acid), Embonic acid, Sodium pamoate

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About This Item

Linear Formula:
C23H14O6Na2
CAS Number:
6640-22-8
Molecular Weight:
432.33
NACRES:
NA.25
PubChem Substance ID:
24898580
UNSPSC Code:
12352106
EC Number:
229-653-1
MDL number:
MFCD00036183
Form:
powder

Key Documents

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InChI

1S/C23H16O6.Na.H/c24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29;;/h1-10,24-25H,11H2,(H,26,27)(H,28,29);;

InChI key

ZRZSXMUASGHHKP-UHFFFAOYSA-N

SMILES string

[Na].OC(=O)c1cc2ccccc2c(Cc3c(O)c(cc4ccccc34)C(O)=O)c1O

form

powder

Quality Level

100

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Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB4921
STBK9979
STBB8715V
STBB8715
100M1510V

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Venkatesh Teja Banala et al.
Advanced healthcare materials, 7(19), e1800300-e1800300 (2018-08-14)
The combination of metabolic modulators with chemotherapy holds vast promise for effective inhibition of tumor progression and invasion. Herein, a ratiometric codelivery platform is developed for metformin (MET), a known metabolic modulator and topotecan (TPT), a chemotherapeutic drug, by engineering
T Saesmaa et al.
Journal of pharmaceutical and biomedical analysis, 8(1), 61-65 (1990-01-01)
The dissolution behaviour of slightly water-soluble embonic acid salts of ampicillin and amoxycillin was studied quantitatively as a function of solution pH (1.15-8.00) using the rotating disk method combined with reversed-phase high-performance liquid chromatography. The dissolution rate of ampicillin embonate
Humphrey Fonge et al.
Bioconjugate chemistry, 18(6), 1924-1934 (2007-10-13)
In a search for an infarct avid tracer agent with improved properties, we have observed that bis-DTPA derivatives of pamoic acid have a high avidity for necrotic tissue. Here, we report the synthesis, radiolabeling, and preliminary evaluation in normal mice
Kristof Prinsen et al.
Bioorganic & medicinal chemistry, 18(14), 5274-5281 (2010-06-29)
In this study, we labeled N,N'-bis(diethylenetriamine pentaacetic acid)-pamoic acid bis-hydrazide (bis-DTPA-PA) with the generator produced PET radionuclide gallium-68 and evaluated 68Ga-bis-DTPA-PA as a potential tracer for in vivo visualization of necrosis by positron emission tomography (PET). Radiolabeling was achieved with
M Jørgensen
Journal of chromatography. B, Biomedical sciences and applications, 716(1-2), 315-323 (1998-11-21)
Pamoic acid is used as a counter ion to obtain long-acting pharmaceutical formulations of certain basic drugs. In order to investigate the pharmacokinetics of pamoic acid, a simple, sensitive and reliable method has been established for the quantitative determination of
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