P5084
PTIO
NO activity inhibitor, powder
Synonym(s):
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide
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About This Item
Empirical Formula (Hill Notation):
C13H17N2O2
CAS Number:
Molecular Weight:
233.29
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:
Product Name
PTIO,
form
powder
Quality Level
storage temp.
2-8°C
SMILES string
CC1(C)N([O])C(c2ccccc2)=[N+]([O-])C1(C)C
InChI
1S/C13H17N2O2/c1-12(2)13(3,4)15(17)11(14(12)16)10-8-6-5-7-9-10/h5-9H,1-4H3
InChI key
DYUUGILMVYJEHY-UHFFFAOYSA-N
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Related Categories
Application
2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIO) has been used as a nitric oxide (NO) scavenger.
Biochem/physiol Actions
2-phenyl-4, 4, 5, 5,-tetramethylimidazoline-1-oxyl 3-oxide (PTIOs) derivatives react with nitric oxide (NO) to yield the corresponding imino nitroxides (PTIs) and nitrogen dioxide (NO2).
A stable radical scavenger for nitric oxide; affects NO without affecting NO synthase; has significant inhibitory activity against NO biological actions.
Stable radical scavenger for nitric oxide without affecting NO synthase; inhibits NO activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Victoria P A Johnstone et al.
Learning & memory (Cold Spring Harbor, N.Y.), 18(10), 625-633 (2011-09-22)
Long-term potentiation (LTP) is an important process underlying learning and memory in the brain. At CA3-CA1 synapses in the hippocampus, three discrete forms of LTP (LTP1, 2, and 3) can be differentiated on the basis of maintenance and induction mechanisms.
Ekaterina Minaeva et al.
PloS one, 12(10), e0186851-e0186851 (2017-10-20)
Truncated hemoglobins constitute a large family, present in bacteria, in archaea and in eukaryotes. However, a majority of physiological functions of these proteins remains to be elucidated. Identification and characterization of a novel role of truncated hemoglobins in the model
Involvement of nitric oxide in oxidative burst, phenylalanine ammonia-lyase activation and Taxol production induced by low-energy ultrasound in Taxus yunnanensis cell suspension cultures.
Wang JW
Nitric Oxide, 15(4), 351-358 (2006)
Mona Soliman et al.
Plants (Basel, Switzerland), 8(12) (2019-12-07)
Nitric oxide (NO) at optimal levels is considered beneficial to plant functioning. The present study was carried out to investigate the role of exogenously applied NO (100 and 150 µM sodium nitropurusside, SNP) in amelioration of nickel (Ni)-mediated oxidative effects
Reactions of PTIO and carboxy-PTIO with *NO, *NO2, and O2-*.
Goldstein S
The Journal of Biological Chemistry, 278 (51), 50949-50955 (2003)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| P5084-100MG | 04061834375807 |
| P5084-25MG | 04061834375821 |
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