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P5136

Poly-γ-benzyl-L-glutamate

Name: Poly-γ-benzyl-<SC>L</SC>-glutamate
Brand: SIGMA

mol wt 150,000-350,000

Synonym(s):

PBLG

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About This Item

CAS Number:

25014-27-1

UNSPSC Code:

12352202

NACRES:

NA.26

MDL number:

MFCD00166357

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form

powder

Quality Level

200

mol wt

150,000-350,000

color

white to light yellow

storage temp.

−20°C

SMILES string

[N+H3][C@@H](CCC(=O)OCc1ccccc1)C(=O)[O-]

InChI

1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1

InChI key

BGGHCRNCRWQABU-JTQLQIEISA-N

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Related Categories

Biochemicals

Cell Culture Supplements & Reagents

Amino Acids – Building Blocks of Life Science

Chemistry & Biochemicals

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number

0000516181

0000430897

0000368680

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Biodegradable cationic PEG-PEI-PBLG hyperbranched block copolymer: synthesis and micelle characterization.

Hua Yu Tian et al.

Biomaterials, 26(20), 4209-4217 (2005-02-03)

A novel amphiphilic biodegradable cationic hyperbranched poly(ethylene glycol)-polyethylenimine-poly(gamma-benzyl L-glutamate) (PEG-PEI-PBLG) block copolymer was successfully synthesized by ring-opening polymerization (ROP) of N-carboxyanhydride of gamma-benzyl-L-glutamate (BLG-NCA) with PEG-PEI as a macroinitiator. PEG-PEI was firstly prepared by coupling of PEG and PEI using

All-atom molecular dynamics study of a spherical micelle composed of N-acetylated poly(ethylene glycol)-poly(gamma-benzyl L-glutamate) block copolymers: a potential carrier of drug delivery systems for cancer.

Hiroshi Kuramochi et al.

The journal of physical chemistry. B, 113(46), 15181-15188 (2009-10-28)

An all-atom molecular dynamics simulation of a spherical micelle composed of amphiphilic N-acetylated poly(ethylene glycol)-poly(gamma-benzyl L-glutamate) (PEG-PBLG-Ac) block copolymers was performed in aqueous solution at 298.15 K and 1 atm. Such copolymers have received considerable attention as carriers in drug

Synthesis and characterization of a block copolymer containing regioregular poly(3-hexylthiophene) and poly(γ-benzyl-L-glutamate).

Nadia Hundt et al.

Macromolecular rapid communications, 32(3), 302-308 (2011-03-25)

Poly(3-hexylthiophene)-b-poly(γ-benzyl-L-glutamate) (P3HT-b-PBLG) rod-rod diblock copolymer was synthesized by a ring-opening polymerization of γ-benzyl-L-glutamate-N-carboxyanhydride using a benzylamine-terminated regioregular P3HT macroinitiator. The opto-electronic properties of the diblock copolymer have been investigated. The P3HT precursor and the P3HT-b-PBLG have similar UV-Vis spectra both

Synthesis and characterization of functionalized poly(gamma-benzyl-L-glutamate) derivates and corresponding nanoparticles preparation and characterization.

Freimar Segura-Sánchez et al.

International journal of pharmaceutics, 387(1-2), 244-252 (2009-12-17)

For being fully efficient a targeted delivery system should associate simultaneously multiple functionalities. In this context, the association of several polymeric materials to form composite multifunctional particles can be foreseen. The present work describes the synthesis of different derivates of

Synthesis and characterization of surface-modified PBLG nanoparticles for bone targeting: in vitro and in vivo evaluations.

Ipek Ozcan et al.

Journal of pharmaceutical sciences, 100(11), 4877-4887 (2011-06-24)

In this study, poly(γ-benzyl-l-glutamate) (PBLG) polypeptide derivatives were synthesized by ring-opening polymerization of amino acid N-carboxyanhydride using selected amine-terminated initiators. Alendronate, a targeting moiety that has a strong affinity for bone, was conjugated to PBLG. Monomethoxy polyethylene glycol (PEG) was

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Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Global Trade Item Number

SKU	GTIN
P5136-1G	04061826686263

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