P5267
L-Proline p-nitroanilide trifluoroacetate salt
≥99% (TLC), suitable for ligand binding assays
Synonym(s):
N-(4-Nitrophenyl)pyrrolidine-2-carboxamide, P-pNA, Pro-pNA
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About This Item
Empirical Formula (Hill Notation):
C11H13N3O3 · C2HF3O2
CAS Number:
Molecular Weight:
349.26
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
MDL number:
Product Name
L-Proline p-nitroanilide trifluoroacetate salt, prolyl aminopeptidase substrate
Quality Segment
assay
≥99% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to yellow
storage temp.
2-8°C
SMILES string
OC(=O)C(F)(F)F.[O-][N+](=O)c1ccc(NC(=O)[C@@H]2CCCN2)cc1
InChI
1S/C11H13N3O3.C2HF3O2/c15-11(10-2-1-7-12-10)13-8-3-5-9(6-4-8)14(16)17;3-2(4,5)1(6)7/h3-6,10,12H,1-2,7H2,(H,13,15);(H,6,7)/t10-;/m0./s1
InChI key
KYRVEVYREUUAKH-PPHPATTJSA-N
General description
Proline p-nitroanilide (P-pNA) is a colorimetric substrate for prolyl aminopeptidase (proline iminopeptidase), an enzyme that releases proline from the N-terminus of small peptides.
Application
L-Proline p-nitroanilide trifluoroacetate salt has also been used as a monopeptide substrate for measuring the amidolytic activity of fibrillated peptide catalyst, PC4.
Proline p-nitroanilide (P-pNA) has been used as a substrate for prolyl aminopeptidase (proline iminopeptidase) from cabbage leaves.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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