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P5660

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain

≥95% (TLC), Procoagulant and Hemostatic regulator, powder

Synonym(s):

1,2-Diacyl-sn-glycero-3-phospho-L-serine, L-α-Phosphatidyl-L-serine sodium salt

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About This Item

UNSPSC Code:
12352200
PubChem Substance ID:
24898688
NACRES:
NA.77
MDL number:
MFCD00077390
Assay:
≥95% (TLC)
Form:
powder
Quality level:
200
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Product Name

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain, ≥95% (TLC)

Quality Level

200

assay

≥95% (TLC)

form

powder

storage temp.

−20°C

SMILES string

[Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C42H82NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-40(44)50-35-38(36-51-54(48,49)52-37-39(43)42(46)47)53-41(45)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h38-39H,3-37,43H2,1-2H3,(H,46,47)(H,48,49);/q;+1/p-1/t38-,39+;/m1./s1

InChI key

SJRBMGBLPUBGJL-MBAWARMDSA-M

Related Categories

General description

Phosphatidylserine is an anionic phospholipid, which is found on the plasma membrane. Exposure of phosphatidylserine on the surface of plasma membrane stimulates the removal of apoptotic and red blood cells. It regulates the production of thrombin and maintains hemostasis.

Application

3-sn-Phosphatidyl-L-serine sodium salt from bovine brain has been used as a glycosylphosphatidylinositol (GPI)-anchor control.

Biochem/physiol Actions

A slowly metabolized structural phospholipid found mainly in gray matter.

Preparation Note

Washed with EDTA and converted to a sodium salt.

Disclaimer

Solutions exposed to room temperature will decompose about 0.5% per day.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000530646
0000530645
0000530645
0000530646
0000519374

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Phosphatidylserine exposure during apoptosis is a cell-type-specific event and does not correlate with plasma membrane phospholipid scramblase expression
Fadeel B, et al.
Biochemical and Biophysical Research Communications, 266(2), 504-511 (1999)
The role of phosphatidylserine in recognition and removal of erythrocytes.
Kuypers FD
Cellular and molecular biology (Noisy-le-Grand, France), 50(2), 147-158 (2004)
Exposure of platelet membrane phosphatidylserine regulates blood coagulation
Lentz BR
Progress in Lipid Research, 42(5), 423-438 (2003)
TIMP-1-GPI in combination with hyperthermic treatment of melanoma increases sensitivity to FAS-mediated apoptosis
Djafarzadeh R, et al.
Cancer Immunology, Immunotherapy, 58(3), 361-361 (2009)
Julien Perino et al.
Antiviral research, 89(1), 89-97 (2010-11-26)
Vaccinia virus (VACV) was used as a surrogate of Variola virus (genus Orthopoxvirus), the causative agent of smallpox, to study orthopoxvirus infection via the respiratory airway. Lung surfactant, a physiological barrier to infection encountered by the virus, is predominantly composed
View All Related Papers

Global Trade Item Number

SKUGTIN
P5660-5MG04061834392194
P5660-100MG04061834392170
P5660-25MG04061834392187

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