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P5960

Sigma-Aldrich

L-Pyroglutamic acid

BioXtra

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Synonym(s):
(S)-(−)-2-Pyrrolidone-5-carboxylic acid, (S)-5-Oxo-2-pyrrolidinecarboxylic acid
Empirical Formula (Hill Notation):
C5H7NO3
CAS Number:
98-79-3
Molecular Weight:
129.11
Beilstein:
82132
EC Number:
202-700-3
MDL number:
MFCD00005272
PubChem Substance ID:
24898722
NACRES:
NA.26

product line

BioXtra

Quality Level

200

Assay

≥97% (titration)

form

powder

technique(s)

cell culture | plant: suitable

impurities

≤0.0005% Phosphorus (P)

ign. residue

≤0.1%

color

white

mp

160-163 °C (lit.)

solubility

H2O: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

SMILES string

OC(=O)[C@@H]1CCC(=O)N1

InChI

1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

InChI key

ODHCTXKNWHHXJC-VKHMYHEASA-N

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Related Categories

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H318 - H412

Hazard Classifications

Aquatic Chronic 3 - Eye Dam. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Li-Hui Sun et al.
Chemical communications (Cambridge, England), 47(36), 10136-10138 (2011-08-11)
The chiral N-heterocyclic carbene bearing a proximal hydroxy group derived from L-pyroglutamic acid was found to be an efficient catalyst for the [3+2] annulation of enals and isatins to give the corresponding spirocyclic oxindolo-γ-butyrolactones in good yield with good diastereo-
Franz Gruber et al.
Current biology : CB, 23(6), 507-514 (2013-03-13)
Motivation controls behavior [1]. A variety of food-related behaviors undergo motivational modulation by hunger, satiety, and other states [2-4]. Here we searched for critical satiation factors modulating approach to an odor associated with sugar reward in Drosophila melanogaster. We selectively
P J Caspers et al.
The Journal of investigative dermatology, 116(3), 434-442 (2001-03-07)
Confocal Raman spectroscopy is introduced as a noninvasive in vivo optical method to measure molecular concentration profiles in the skin. It is shown how it can be applied to determine the water concentration in the stratum corneum as a function
M H Creer et al.
Clinical chemistry, 35(4), 684-686 (1989-04-01)
Pyroglutamic acidemia, a rare metabolic disorder, usually appears in infancy. It is characterized by retardation, ataxia, hemolytic anemia, and chronic acidosis and is caused by a marked deficiency of glutathione synthetase (EC 6.3.2.3) activity. This disease is inherited as an
Manuel Weber et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(46), 14792-14804 (2012-09-29)
The development and further evolution of the first catalytic asymmetric conjugate additions of azlactones as activated amino acid derivatives to enones is described. Whereas the first-generation approach started from isolated azlactones, in the second-generation approach the azlactones could be generated
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