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P7547

Phentolamine hydrochloride

Name: Phentolamine hydrochloride
Brand: SIGMA

≥98% (TLC), α-adrenoceptor antagonist, powder

Synonym(s):

2-[N-(3-Hydroxyphenyl)-p-toluidinomethyl]-2-imidazolidine hydrochloride, 3-[[(4,5-Dihydro-1H-imidazol-2-yl)-methyl](4-methylphenyl)-amino]-phenol monohydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₁₉N₃O · HCl

CAS Number:

73-05-2

Molecular Weight:

317.81

NACRES:

NA.77

PubChem Substance ID:

24898856

UNSPSC Code:

12352116

EC Number:

200-793-5

MDL number:

MFCD00079268

Beilstein/REAXYS Number:

3764617

Assay:

≥98% (TLC)

Form:

powder

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Properties

Product Name

Phentolamine hydrochloride, ≥98% (TLC), powder

Quality Segment

200

assay

≥98% (TLC)

form

powder

color

white to off-white

solubility

ethanol: 14 mg/mL, H₂O: 20 mg/mL, H₂O: unstable (prepare immediately prior to use)

originator

Novartis

SMILES string

Cl[H].Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3

InChI

1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H

InChI key

TUEJFGFQYKDAPM-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Description

Biochem/physiol Actions

α-adrenoceptor antagonist; peripheral vasodilator.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Protect From Light.

pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c