P7780
Propionylpromazine hydrochloride
Synonym(s):
Propiopromazine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C20H24N2OS · HCl
CAS Number:
Molecular Weight:
376.94
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
38502
InChI
1S/C20H24N2OS.ClH/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1H
SMILES string
Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1
InChI key
ZFWVWZODBGTOIL-UHFFFAOYSA-N
form
powder
storage temp.
2-8°C
Quality Level
Gene Information
human ... DRD2(1813)
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Biochem/physiol Actions
Phenothiazine antipsychotic; D2 dopamine receptor antagonist.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Thomas M Primus et al.
Pest management science, 61(6), 605-611 (2005-01-26)
An analytical method to evaluate propionylpromazine hydrochloride (PPZHCl) in tranquilizer formulations was developed using high-performance liquid chromatography (HPLC). During analysis of aged quality-control samples, a previously unreported chromatographic response was observed at a shorter retention time than PPZHCl. Further investigation
M N Mgasa et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 36(3), 225-229 (1989-03-01)
Eighteen dogs of Tanzanian breeds divided into three groups of 6 were anaesthetized using either azaperone-metomidate (2 mg/kg, i.m. and 10 mg/kg i.p., respectively), propionyl promazine-xylazine-metomidate (2 mg/kg i.m., 1 mg/kg i.m. and 10 mg/kg i.p., respectively), or xylazine-ketamine (1
E A Dewey et al.
The Cornell veterinarian, 74(1), 38-49 (1984-01-01)
The metabolism of propionylpromazine in the horse was studied. Although propionylpromazine is not currently approved or recommended for use in horses, it has been used illegally to alter their performance. Propionylpromazine hydrochloride was administered intramuscularly at clinical and subclinical doses.
[Use of a propionylpromazine and meperidine combination in thiopental sodium anesthesia in horses].
R Deppe et al.
Zentralblatt fur Veterinarmedizin. Reihe A, 32(1), 59-67 (1985-01-01)
D Wrońska et al.
Endokrynologia Polska, 42(4), 567-574 (1991-01-01)
The study was aimed at the evaluation of propiopromazine (Combelen, Bayer), a derivative of phenothiazine, as an agent lowering in sheep the response to stress. The stress of emotional origin was induced in sheep by the isolation from herd lasting
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