Key Documents

View All Documentation

P8013

Pargyline hydrochloride

Name: Pargyline hydrochloride
Brand: SIGMA

synthetic, 98% (TLC), MAO-B inhibitor, powder or crystals

Synonym(s):

N-Methyl-N-(2-propynyl)benzylamine hydrochloride, N-Methyl-N-propargylbenzylamine hydrochloride

Select a Size

Change View

About This Item

Linear Formula:

C₆H₅CH₂N(CH₃)CH₂C≡CH·HCl

CAS Number:

306-07-0

Molecular Weight:

195.69

NACRES:

NA.77

PubChem Substance ID:

24278153

UNSPSC Code:

12352200

EC Number:

206-175-1

MDL number:

MFCD00012492

Beilstein/REAXYS Number:

3699487

Assay:

98% (TLC)

Form:

powder or crystals

Quality level:

200

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Product Name

Pargyline hydrochloride,

biological source

synthetic

Quality Level

200

assay

98% (TLC)

form

powder or crystals

mp

160-163 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

Cl[H].CN(CC#C)Cc1ccccc1

InChI

1S/C11H13N.ClH/c1-3-9-12(2)10-11-7-5-4-6-8-11;/h1,4-8H,9-10H2,2H3;1H

InChI key

BCXCABRDBBWWGY-UHFFFAOYSA-N

Gene Information

human ... MAOA(4128), MAOB(4129)

Related Categories

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

Application

Pargyline hydrochloride has been used:

as a histone demethylase inhibitor to treat monocytes to investigate whether various inhibitors affect training
to maximize uptake into dopaminergic neurons (DA) neurons in experimental rats,
to study its effect on discolouration of medullary tissues of sclerotia of S. sclerotiorum

Biochem/physiol Actions

Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.

Selective MAO-B inhibitor.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Biochemical Pathway for the Formation of Abnormal Sclerotia of Sclerotinia sclerotiorum

Huang HC and Yeung JM

Plant Pathology, 11(1), 2-2 (2002)

Trained immunity or tolerance: opposing functional programs induced in human monocytes after engagement of various pattern recognition receptors

Ifrim DC, et al.

Clinical and Vaccine Immunology : CVI, 21(4), 534-545 (2014)

Resonant antidromic cortical circuit activation as a consequence of high-frequency subthalamic deep-brain stimulation

Li S, et al.

Journal of Neurophysiology, 98(6), 3525-3537 (2007)

An update on antidepressant toxicity: an evolution of unique toxicities to master

Liebelt EL

Clinical Pediatric Emergency Medicine, 9(1), 24-34 (2008)

Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes.

Erica P Cai et al.

Nature metabolism, 2(9), 934-945 (2020-07-29)

Type 1 diabetes (T1D) is caused by the autoimmune destruction of pancreatic beta cells. Pluripotent stem cells can now be differentiated into beta cells, thus raising the prospect of a cell replacement therapy for T1D. However, autoimmunity would rapidly destroy

View All Related Papers

Global Trade Item Number

SKU	GTIN
P8013-5G	04061832948508
P8013-1G	04061834400769
P8013-500MG	04061832948492

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service