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Merck
CN

P8180

DL-α-Phosphatidylcholine, distearoyl

≥98%

Synonym(s):

1,2-Distearoyl-rac-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C44H88NO8P
CAS Number:
Molecular Weight:
790.15
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
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assay

≥98%

form

powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OCC(COP(O)(=O)OCC[N](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C44H89NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3,(H,48,49)

InChI key

OIBGDBRKAPVPMZ-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Mette Marie Bruun Nielsen et al.
Langmuir : the ACS journal of surfaces and colloids, 29(5), 1525-1532 (2013-01-04)
Imaging ellipsometry (IE) has been applied to generate laterally resolved thickness maps of spin-coated membranes in both the dry and fully hydrated state. Spin-coating offers a convenient preparation method for stacked supported membranes, and in-depth thickness maps for such films
Erin K Nyren-Erickson et al.
Langmuir : the ACS journal of surfaces and colloids, 28(46), 16115-16125 (2012-10-30)
Though the aggregation of glycosaminoglycans (GAGs) in the presence of liposomes and divalent cations has been previously reported, the effects of different GAG species and minor changes in GAG composition on the aggregates that are formed are yet unknown. If
M Delwar Hussain et al.
International journal of pharmaceutics, 422(1-2), 290-294 (2011-11-22)
Solid dispersions of ibuprofen with various phospholipids were prepared, and the effect of phospholipids on the in vitro dissolution and in vivo gastrointestinal toxicity of ibuprofen was evaluated. Most phospholipids improved the dissolution of ibuprofen; dimyristoylphosphatidyl-glycerol (DMPG) had the greatest
Shubhadeep Banerjee et al.
International journal of pharmaceutics, 436(1-2), 786-797 (2012-08-14)
pH-responsive polymers render liposomes pH-sensitive and facilitate the intracellular release of encapsulated payload by fusing with endovascular membranes under mildly acidic conditions found inside cellular endosomes. The present study reports the use of high-molecular weight poly(styrene-co-maleic acid) (SMA), which exhibits
Siddikuzzaman et al.
International immunopharmacology, 14(4), 570-579 (2012-10-02)
The purpose of this study was to investigate whether all trans retinoic acid (ATRA) incorporated in liposome composed of distearoylphosphatidylcholine (DSPC/cholesterol) could inhibit the metastatic lung cancer in mice more efficiently than free ATRA. Metastatic lung cancer model was developed

Global Trade Item Number

SKUGTIN
P8180-100MG04061834401124

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