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P8810

Sigma-Aldrich

Phytic acid sodium salt hydrate

from rice

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Synonym(s):
myo-Inositol hexakis(dihydrogen phosphate), Inositol hexakisphosphate, Inositol hexaphosphoric acid, InsP6
Empirical Formula (Hill Notation):
C6H18O24P6 · xNa+ · yH2O
CAS Number:
14306-25-3
Molecular Weight:
660.04 (anhydrous free acid basis)
EC Number:
238-242-6
PubChem Substance ID:
24898983
NACRES:
NA.25

biological source

rice

form

powder

composition

Sodium (Na), ≥5 mol/mol

solubility

water: soluble

cation traces

Ca: ≤2%

storage temp.

room temp

SMILES string

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)O[C@H]1[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@@H](OP([O-])([O-])=O)[C@@H]1OP([O-])([O-])=O

InChI

1S/C6H18O24P6.12Na/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15;;;;;;;;;;;;/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24);;;;;;;;;;;;/q;12*+1/p-12

InChI key

KETSPIPODMGOEJ-UHFFFAOYSA-B

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General description

Phytic acid is a major determinant of zinc bioavailability.

Application

Phytic acid has been used in a study to assess the common bean′s potential as a vehicle for iron biofortification. It has also been used in a study to investigate the effects of antinutritional factors on plasma lipoprotein levels.

Biochem/physiol Actions

Phytic acid is present in all eukaryotic cells. In plants, it is known to function as a [PO4]3− storage depot and precursor for other inositol phosphates and pyrophosphates. Its high surface negative charge makes it a potent chelator of divalent and trivalent cations in vitro, and it is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, phytic acid acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).

Analysis Note

Inorganic phosphorus content is not determined on this product.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Niharika Sashidhar et al.
The New phytologist, 225(5), 2022-2034 (2019-10-28)
Brassica napus (oilseed rape) is an important oil crop in temperate regions, which originated from hybridization of Brassica oleracea and Brassica rapa. Owing to its polyploidy, the functional study of single genes is cumbersome. Phytic acid is considered as an
Zelalem Eshetu Bekalu et al.
PloS one, 12(5), e0176838-e0176838 (2017-05-05)
In the current study, we report for the first time that grain components of barley, rice, wheat and maize can inhibit the activity of Aspergillus ficuum phytase. The phytase inhibition is dose dependent and varies significantly between cereal species, between
Petra Bukovská et al.
Frontiers in microbiology, 7, 711-711 (2016-06-01)
Large fraction of mineral nutrients in natural soil environments is recycled from complex and heterogeneously distributed organic sources. These sources are explored by both roots and associated mycorrhizal fungi. However, the mechanisms behind the responses of arbuscular mycorrhizal (AM) hyphal
Claus Krogh Madsen et al.
Analytical biochemistry, 578, 7-12 (2019-05-06)
Phytases are involved in the phosphate acquisition and remobilization in plants, microbes and animals. They have become important technical enzymes in the feed industry and are used to make phosphate, present in animal feed as phytate, available for monogastric animal
Nicolai Petry et al.
The Journal of nutrition, 142(3), 492-497 (2012-02-03)
Biofortification of plants is a new approach to combat iron deficiency. Common beans (Phaseolus vulgaris) can be bred with a higher iron concentration but are rich in iron absorption inhibitors, phytic acid (PA), and polyphenols (PP). To evaluate the potential
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