P8861
Pyrrolnitrin
from Pseudomonas cepacia, ≥98% (HPLC), antibiotic, solid
别名:
3-Chloro-4-(3-chloro-2-nitrophenyl)pyrrole
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
EC Number:
213-812-7
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
产品名称
Pyrrolnitrin from Pseudomonas cepacia, ≥98% (HPLC), solid
Quality Segment
assay
≥98% (HPLC)
form
solid
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
shipped in
wet ice
storage temp.
−20°C
SMILES string
[O-][N+](=O)c1c(Cl)cccc1-c2c[nH]cc2Cl
InChI
1S/C10H6Cl2N2O2/c11-8-3-1-2-6(10(8)14(15)16)7-4-13-5-9(7)12/h1-5,13H
InChI key
QJBZDBLBQWFTPZ-UHFFFAOYSA-N
Application
Pyrrolnitrin from Pseudomonas cepacia has been used as a standard in the detection of pyrrolnitrin in Serratia marcescens cell culture extract.
Biochem/physiol Actions
Pyrrolnitrin is a metabolite, produced by Pseudomonas sp.
The purified antibiotic has strong antifungal activity and is less efficient against bacteria or yeast.
Pyrrolnitrin blocks the terminal electron transport between succinate or reduced NADH and coenzyme Q. In mitochondria preparations of S. cerevisiae, the antibiotic inhibited succinate oxidase, NADH oxidase, succinate cythochrome C reductase, and NADH-cytochrome C reductase. Pyrrolnitrin is involved in many cellular processes such as oxidative stress, electron transport, DNA and RNA synthesis.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves